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Case: Indeterminate for UIP

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Another patient with mild fibrosis here

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and this is pretty mild, so peripheral bas

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or predominant, I don't think I see any traction

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bronchiectasis or bronchiectasis,

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at least not with high confidence.

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And so this is just mild peripheral

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and basler reticular abnormality

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and so I don't know what's going on.

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I just wouldn't feel confident conice one way or another.

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We can obviously look at the soft tissue windows

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for other abnormalities.

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So those are guys with Hawkeye.

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You guys probably notice that the esophagus is dilated.

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So we're gonna do a, a deep dive.

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We're gonna look at the serologies

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or at least our ask our pulmonologist rheumatologist

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to look at serologies to assess for connect disease.

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And we're gonna do a detailed history

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and physical to look for signs

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and symptoms of connect disease,

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but based purely on imaging.

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This is a hard pattern because it's so mild.

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So what do you do with this? This is one

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where I would probably call it just indetermined if UIP,

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but I probably, I would bring the patient back in a year.

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'cause this is so other people might just call this,

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well this is interstitial lung abnormality.

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I know I haven't really, we haven't really

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talked about that in detail.

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But bottom line, interstitial lung abnormality

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and indetermined, if UIP are

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somewhat related in determine if UIP is sort

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of just throwing for hands saying

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I don't know what's going on.

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And that could be either, because again,

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the disease is very mild like this

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or it can be in cases where the pattern is just very complex

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or confusing In ILA interstitial lung abnormality,

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these are cases where you have very mild peripheral

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reticulation with

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or without con competent pulmonary fibrosis

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where you're not sure if it's static scarring.

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So like maybe the patient had a severe pneumonia,

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severe aspiration, which cause a reticular abnormality

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or it's early progressive pulmonary fibrosis

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or early UIP idiopathic pulmonary fibrosis.

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So that's, that's sort of the dichos decision point.

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So is this gonna be just scarring, which is static

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or a pulmonary fibrosis, which can get worse.

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And so we call that interstitial lung abnormality.

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We'll talk about this phenomenon, uh, few lectures from now.

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But for this case, uh, in the schema

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of a UIP diagnostic approach,

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we're gonna call this indeterminate for UIP.

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And again, I would bring this patient back in a year

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'cause we would do the same thing for patients

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with interstitial lung abnormality in addition

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to correlating with longitudinal pulmonary function testing.

Report

Faculty

Jonathan H. Chung, MD

Professor of Radiology and Division Chief of Cardiothoracic Imaging

UCSD - University of California San Diego

Tags

Syndromes

Non-infectious Inflammatory

Lungs

Idiopathic

Drug related

Chest CT

Chest

CT