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Summary of Diffuse Cystic Lung Disease

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So let's wrap up.

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So we have our four choices for differential diagnosis

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for diffuse cystic lung disease at most centers.

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And so remember lamb, we're talking about thin walled,

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pretty cyst, diffuse distribution round

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and oval intervening.

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Lung should be normal. Remember lamb can be either related

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to tube sclerosis

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or it can come, um, without

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that underlying disease abnormality.

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And so in both these cases, you're gonna look for angio,

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my lipomas in the upper abdomen.

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Even in patients who have isolated lam

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and not TS related lam,

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they can still get angio myel lipomas.

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Every once in a while you're gonna see some scattered subs,

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solid nodules throughout the lungs, usually subs solid,

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very small and often oftentimes innumerable.

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And so in the setting of lamb, you should be thinking,

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especially TS lamb.

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You should be thinking about multifocal micro nodular

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pneumococci hyperplasia.

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Some people would just call it pneumococci hyperplasia,

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but we can see those as well.

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Uh, probably worth following them at least a little bit

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to make sure that there's no adenocarcinoma in any

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of these more dominant nodules.

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TLCH, we talked about that.

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It's just completely different from the other, uh,

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diffuse cystic lung disease.

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So the cytal walls can be thin

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or thick, they're ugly, they're upper lung preponderant.

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They spare the schizophrenic angles can be oftentimes

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bizarre shaped, very, very different.

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And heterogeneous, remember

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that they emanate from those central lo nodules.

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And you should be looking

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for these cheerios like small cavitary

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nodules and an end stage.

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They can give you this burnt out appearance,

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that complex pattern of some upper lung preponderant,

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fibrosis, emphysema, diffuse cystic lung disease,

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and sometimes some scattered central lobular nodules.

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So pretty specific for P-P-L-C-H.

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Again, if there's that relative basal sparing in somewhat

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strong smoking related history, LIP.

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In adults, we're gonna see that most common Sjogren's

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syndrome and sometimes even deficiencies.

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These are basar predominant cyst. They're pretty cysts.

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Look for peron ster and subpleural cyst.

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Um, every once in a while you're gonna see some concomitant

2:01

inflammation, but in my

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clinical practice, that's not that common.

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LIP and bird hug debate look very similar.

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Bird Hug Bay also gives you thin walled cyst.

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But remember, look for those renal tumors.

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So bird hug debase syndrome also predispose you

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to renal tumors, renal cell carcinomas and oncocytoma.

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And then for bird hug debase syndrome.

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The per mediastinals are quite characteristic.

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Thank you very much. I.

Report

Faculty

Jonathan H. Chung, MD

Professor of Radiology and Division Chief of Cardiothoracic Imaging

UCSD - University of California San Diego

Tags

Syndromes

Non-infectious Inflammatory

Neoplastic

Lungs

Chest CT

Chest

CT

Acquired/Developmental