Training Collections
Library Memberships
On-demand course library with video lectures, expert case reviews, and more
Fellowship Certificate™ Programs
Practice-focused training programs designed to help you gain experience in a specific subspecialty area.
Ultimate Learning Pass
Unlock access to our full Course Library and all self-paced Fellowships.
Continuing Medical Education (State CME)
Complete all of your state CME requirements in one convenient place.
Noon Conference (Free)
Get access to free live lectures, every week, from top radiologists.
Case of the Week (Free)
Get a free weekly case delivered right to your inbox.
Case Crunch: Rapid Case Review (Free)
Register for free live board reviews.
Dr. Resnick's MSK Conference
Learn directly from the MSK Master himself.
Lower Extremities MRI Conference
Musculoskeletal Imaging
For Training Programs
Supplement your training program with case-based learning for residents, registrars, fellows, and more.
For Private Practices
Upskill in high growth, advanced imaging areas.
Compliance
NewTrack, fulfill, and report on all your radiologists' credentialing and licensing requirements.
Emergency Call Prep
Prepare trainees to be on call for the emergency department with this specialized training series.
Training Collections
Library Memberships
On-demand course library with video lectures, expert case reviews, and more
Fellowship Certificate™ Programs
Practice-focused training programs designed to help you gain experience in a specific subspecialty area.
Ultimate Learning Pass
Unlock access to our full Course Library and all self-paced Fellowships.
Continuing Medical Education (State CME)
Complete all of your state CME requirements in one convenient place.
Noon Conference (Free)
Get access to free live lectures, every week, from top radiologists.
Case of the Week (Free)
Get a free weekly case delivered right to your inbox.
Case Crunch: Rapid Case Review (Free)
Register for free live board reviews.
Dr. Resnick's MSK Conference
Learn directly from the MSK Master himself.
Lower Extremities MRI Conference
Musculoskeletal Imaging
For Training Programs
Supplement your training program with case-based learning for residents, registrars, fellows, and more.
For Private Practices
Upskill in high growth, advanced imaging areas.
Compliance
NewTrack, fulfill, and report on all your radiologists' credentialing and licensing requirements.
Emergency Call Prep
Prepare trainees to be on call for the emergency department with this specialized training series.
3 topics, 15 min. of video
17 topics, 59 min. of video
Introduction to Fibrotic Lung Disease
3 m.Practical Approach to Pulmonary Fibrosis
6 m.Usual Interstitial Pneumonia (UIP): The 800lb Gorilla
3 m.UIP Diagnostic Criteria
2 m.Typical UIP and Probable UIP
6 m.Nonspecific Interstitial Pneumonia (NSIP)
10 m.Fibrotic Hypersensitivity Pneumonitis (fHP)
10 m.Case: Classic UIP (IPF) and Tracheobronchomalacia
4 m.Case: Fibrotic HP
2 m.Case: fHP pattern in CTD
4 m.Case: Asbestosis
4 m.Case: UIP with NSIP Elements in IPAF
4 m.Case: Classic UIP
2 m.Case: Indeterminate for UIP
3 m.Case: Combined NSIP and Organizing Pneumonia
2 m.Case: NSIP in IPAF
2 m.Case: NSIP in Systemic Sclerosis (SSc)
2 m.15 topics, 35 min. of video
Introduction to Diffuse Nodular Lung Disease
4 m.Secondary Pulmonary Lobule Anatomy
2 m.Nodular Pattern Taxonomy
4 m.Random Nodules
5 m.Perilymphatic Nodules
6 m.Centrilobular Nodules
7 m.Case: Mild Perilymphatic Nodularity in Sarcoidosis
2 m.Case: Sarcoidosis - Perilymphatic Nodularity
2 m.Case: Fibrotic Sarcoidosis with Perilymphatic Nodularity
2 m.Case: Random Nodules in Histoplasmosis
2 m.Case: Adenocarcinoma
2 m.Case: Hypersensitivity Pneumonitis with Centrilobular Nodules
2 m.Case: Aspiration with Centrilobular Nodules
1 m.Case: Centrilobular Nodularity in Respiratory Bronchiolitis (RB)
2 m.Summary of Diffuse Nodular Lung Disease
1 m.16 topics, 30 min. of video
Introduction to Diffuse Cystic Lung Disease
2 m.Diagnostic Approach to Cystic Lung Disease
6 m.Emphysema
2 m.Pulmonary Langerhans Cell Histiocytosis (PLCH)
5 m.Lymphangioleiomyomatosis (LAM)
2 m.Lymphocytic Interstitial Pneumonia (LIP)
4 m.Birt‑Hogg‑Dubé Syndrome
3 m.Case: LAM with Right Pleural Thickening
2 m.Case: LAM With Possible Chronic Pneumothorax
1 m.Case: LAM With Chylous Effusions
1 m.Case: LIP Non-Specific
2 m.Case: Classic LIP
2 m.Case: Birt‑Hogg‑Dubé Mild
1 m.Case: Birt‑Hogg‑Dubé Pneumothorax
1 m.Case: Classic LCH
2 m.Summary of Diffuse Cystic Lung Disease
3 m.5 topics, 8 min. of video
3 topics, 3 min. of video
1 topic
0:01
So let's wrap up.
0:02
So we have our four choices for differential diagnosis
0:06
for diffuse cystic lung disease at most centers.
0:09
And so remember lamb, we're talking about thin walled,
0:12
pretty cyst, diffuse distribution round
0:14
and oval intervening.
0:15
Lung should be normal. Remember lamb can be either related
0:20
to tube sclerosis
0:22
or it can come, um, without
0:24
that underlying disease abnormality.
0:27
And so in both these cases, you're gonna look for angio,
0:29
my lipomas in the upper abdomen.
0:30
Even in patients who have isolated lam
0:33
and not TS related lam,
0:34
they can still get angio myel lipomas.
0:37
Every once in a while you're gonna see some scattered subs,
0:40
solid nodules throughout the lungs, usually subs solid,
0:42
very small and often oftentimes innumerable.
0:46
And so in the setting of lamb, you should be thinking,
0:48
especially TS lamb.
0:49
You should be thinking about multifocal micro nodular
0:51
pneumococci hyperplasia.
0:53
Some people would just call it pneumococci hyperplasia,
0:55
but we can see those as well.
0:57
Uh, probably worth following them at least a little bit
0:59
to make sure that there's no adenocarcinoma in any
1:02
of these more dominant nodules.
1:05
TLCH, we talked about that.
1:06
It's just completely different from the other, uh,
1:07
diffuse cystic lung disease.
1:09
So the cytal walls can be thin
1:11
or thick, they're ugly, they're upper lung preponderant.
1:14
They spare the schizophrenic angles can be oftentimes
1:17
bizarre shaped, very, very different.
1:19
And heterogeneous, remember
1:21
that they emanate from those central lo nodules.
1:24
And you should be looking
1:25
for these cheerios like small cavitary
1:27
nodules and an end stage.
1:28
They can give you this burnt out appearance,
1:30
that complex pattern of some upper lung preponderant,
1:33
fibrosis, emphysema, diffuse cystic lung disease,
1:37
and sometimes some scattered central lobular nodules.
1:40
So pretty specific for P-P-L-C-H.
1:42
Again, if there's that relative basal sparing in somewhat
1:46
strong smoking related history, LIP.
1:49
In adults, we're gonna see that most common Sjogren's
1:51
syndrome and sometimes even deficiencies.
1:53
These are basar predominant cyst. They're pretty cysts.
1:56
Look for peron ster and subpleural cyst.
1:58
Um, every once in a while you're gonna see some concomitant
2:01
inflammation, but in my
2:02
clinical practice, that's not that common.
2:04
LIP and bird hug debate look very similar.
2:06
Bird Hug Bay also gives you thin walled cyst.
2:08
But remember, look for those renal tumors.
2:10
So bird hug debase syndrome also predispose you
2:13
to renal tumors, renal cell carcinomas and oncocytoma.
2:17
And then for bird hug debase syndrome.
2:20
The per mediastinals are quite characteristic.
2:23
Thank you very much. I.
Interactive Transcript
0:01
So let's wrap up.
0:02
So we have our four choices for differential diagnosis
0:06
for diffuse cystic lung disease at most centers.
0:09
And so remember lamb, we're talking about thin walled,
0:12
pretty cyst, diffuse distribution round
0:14
and oval intervening.
0:15
Lung should be normal. Remember lamb can be either related
0:20
to tube sclerosis
0:22
or it can come, um, without
0:24
that underlying disease abnormality.
0:27
And so in both these cases, you're gonna look for angio,
0:29
my lipomas in the upper abdomen.
0:30
Even in patients who have isolated lam
0:33
and not TS related lam,
0:34
they can still get angio myel lipomas.
0:37
Every once in a while you're gonna see some scattered subs,
0:40
solid nodules throughout the lungs, usually subs solid,
0:42
very small and often oftentimes innumerable.
0:46
And so in the setting of lamb, you should be thinking,
0:48
especially TS lamb.
0:49
You should be thinking about multifocal micro nodular
0:51
pneumococci hyperplasia.
0:53
Some people would just call it pneumococci hyperplasia,
0:55
but we can see those as well.
0:57
Uh, probably worth following them at least a little bit
0:59
to make sure that there's no adenocarcinoma in any
1:02
of these more dominant nodules.
1:05
TLCH, we talked about that.
1:06
It's just completely different from the other, uh,
1:07
diffuse cystic lung disease.
1:09
So the cytal walls can be thin
1:11
or thick, they're ugly, they're upper lung preponderant.
1:14
They spare the schizophrenic angles can be oftentimes
1:17
bizarre shaped, very, very different.
1:19
And heterogeneous, remember
1:21
that they emanate from those central lo nodules.
1:24
And you should be looking
1:25
for these cheerios like small cavitary
1:27
nodules and an end stage.
1:28
They can give you this burnt out appearance,
1:30
that complex pattern of some upper lung preponderant,
1:33
fibrosis, emphysema, diffuse cystic lung disease,
1:37
and sometimes some scattered central lobular nodules.
1:40
So pretty specific for P-P-L-C-H.
1:42
Again, if there's that relative basal sparing in somewhat
1:46
strong smoking related history, LIP.
1:49
In adults, we're gonna see that most common Sjogren's
1:51
syndrome and sometimes even deficiencies.
1:53
These are basar predominant cyst. They're pretty cysts.
1:56
Look for peron ster and subpleural cyst.
1:58
Um, every once in a while you're gonna see some concomitant
2:01
inflammation, but in my
2:02
clinical practice, that's not that common.
2:04
LIP and bird hug debate look very similar.
2:06
Bird Hug Bay also gives you thin walled cyst.
2:08
But remember, look for those renal tumors.
2:10
So bird hug debase syndrome also predispose you
2:13
to renal tumors, renal cell carcinomas and oncocytoma.
2:17
And then for bird hug debase syndrome.
2:20
The per mediastinals are quite characteristic.
2:23
Thank you very much. I.
Report
Faculty
Jonathan H. Chung, MD
Professor of Radiology and Division Chief of Cardiothoracic Imaging
UCSD - University of California San Diego
Tags
Syndromes
Non-infectious Inflammatory
Neoplastic
Lungs
Chest CT
Chest
CT
Acquired/Developmental
© 2026 Medality. All Rights Reserved.