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Case: Combined NSIP and Organizing Pneumonia

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So here's a example of

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combined NSIP and op.

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And so if we scroll through, you'll know

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that there's relative subpleural sparing.

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So that's very suggestive.

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NSIP look at this beautiful subpleural sparing there,

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but superimposed on the underlying reticulation

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and ground opacity are more dense areas of consolidation.

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There's concomitant traction, bronchiectasis

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and bronchiectasis as you can see,

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and maybe even the mildest subpleural honeycombing

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within the right lower lobe.

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But this overall pattern would be highly

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inconsistent with UIB.

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This is something else. And so this is a,

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A beautiful example, pretty classic example

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of nonspecific interstitial pneumonitis

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with organizing pneumonia.

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We didn't really talk about organizing pneumonia,

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but organizing pneumonia is not uncommon in the setting

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of connective tissue disease

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and the way it manifests on CT R areas of consolidation,

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which are very commonly para bronchovascular

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or subpleural in distribution.

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But if you see this combined NSIP op pattern,

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you should be thinking about connected tissue disease

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and the highest thing on your differential diagnosis is

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gonna be myositis.

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So Dermatomyositis, polymyositis

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and their cousin, the anti sythes syndrome.

Report

Faculty

Jonathan H. Chung, MD

Professor of Radiology and Division Chief of Cardiothoracic Imaging

UCSD - University of California San Diego

Tags

Syndromes

Non-infectious Inflammatory

Lungs

Chest CT

Chest

CT