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Introduction to Diffuse Nodular Lung Disease

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All right.

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Now let's talk about diffuse nodular lung disease.

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So if

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after this talk you are better able

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to recognize different patterns

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of diffuse nodular lung disease,

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you can put together differential diagnosis based

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on specific patterns.

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And you'll recall imaging

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or clinical findings, which allow you

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to make a specific diagnosis.

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I feel like it would've been successful.

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So where are we going? We're gonna be talking about

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what the heck is diffuse nodule lung disease?

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What are we really talking about here?

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And then we're gonna be talking about the subcategories.

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The subcategories are very helpful if you can get a case

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of diffuse nodule lung disease

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and then subcategorize based on one of these three patterns,

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you can really narrow the differential diagnosis.

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And sometimes you come down to one specific diagnosis

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and then we'll just wrap up.

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So this is pretty cut and dry.

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We're not talking about indeterminate pulmonary nodule.

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We're not talking about flechner,

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lung rads, any of this kind of stuff.

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Uh, that is not the, in the scope here.

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What we're gonna be talking about are these

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innumerable pulmonary nodules.

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People have stopped me and said, you know,

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innumerable, what does that really mean?

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Because if you really want to

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count them, you could count them.

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Well, for me, I would think so.

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If you would have to count more than 30

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or 40 nodules, to me, that's innumerable.

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You don't want to count them, right?

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And you kind of like know when you see it,

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like there's just too many nodules that count.

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Then you're dealing with a case

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of diffuse nodule lung disease.

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And usually these nodules

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and diffuse nodule lung disease are gonna be smaller,

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usually on a scale of four to five millimeters.

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They can be a little larger sometimes,

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but these are the predominant size of nodules.

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Sometimes can be smaller as well.

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And then not always,

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but the vast majority

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of time diffuse nodular lung disease will be bilateral

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and generally symmetric.

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But sometimes they could be a little bit asymmetric in

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setting of perilymphatic nodularity

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and sub cases of central lobular nodularity

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before actually go into the subtypes

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of diffuse nodule lung disease.

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Let's talk about mips.

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And so I think MIPS

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or maximum intensity projection images,

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these are now standard of care, right?

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If your hospital

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or medical center is not routinely doing mips,

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or if you don't have the ability to create MIPS on the fly,

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you probably should reconsider that.

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MIPS are quite helpful. They can be a variable thickness

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variable overlap, but bottom line, you need to do it

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because it'll help you for diffuse nodule lung disease

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if you don't have an AI

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or a vessel subtraction tool

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to help you identify isolated pulmonary nodules.

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I told, I said I wasn't gonna talk about that,

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but I think I, these,

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these mips are helpful for that as well.

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And given the high number of isolated pulmonary nodules

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that we see on chest ET, if you're not doing mips,

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you're doing yourself a disservice.

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You're just slowing yourself down

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and you're making yourself less accurate.

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So, um, I'll get, get off my high horse, uh, bottom line,

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if you're not doing them, do them again.

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I think that, I'm sure 99%

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of places out there are doing these routinely.

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Example of a regular axo image on the left

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and m image on the right is just so much

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Easier. We see more

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nodules per axial slice

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because there are thick slabs of data in there.

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And then it's easier to define where these nodules are

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relative to the underlying secondary pulmonary lobular

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anatomy and the general anatomy

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of the lung parenchyma in terms of subpleural lung

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and bronchovascular tree.

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So, so much better.

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Just if you're dealing with nodules, look at the mips.

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Obviously these regular actually images are valuable

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as well, but you gotta do both.

Report

Faculty

Jonathan H. Chung, MD

Professor of Radiology and Division Chief of Cardiothoracic Imaging

UCSD - University of California San Diego

Tags

Vascular

Syndromes

Non-infectious Inflammatory

Neoplastic

Lungs

Infectious

Drug related

Chest CT

Chest

CT