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Case: Sarcoidosis - Perilymphatic Nodularity

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Another classic example of sarcoidosis.

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This patient's been biopsied, as you can tell,

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there's suture material within the right upper lobe.

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We see nice examples of para bronchovascular

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nodularity within the upper lobes.

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And so we would invoke something called the galaxy sign.

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I don't know if you guys have heard of that,

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the galaxy sign in the setting of many of these nodules.

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Here's a classic example here, right?

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So it's when you see this central nodule

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with these little tentacles of reticulate, nodularity

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almost look like a studded nodule there.

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And so that, especially when it's para bronchovascular,

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like this, highly suggestive of a ulous process.

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And so the classic ulous process to do this is sarcoidosis.

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And so then if we scroll through the rest of the CT scan,

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we're gonna see that there's a basal gradient

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or probably an upper lung gradient

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where the lung bases are relatively spared.

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There's still some nodules there,

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but the majority of these nodules,

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which again are paralympic, right, likes the fissures,

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likes the sub lung, likes the bronchovascular tree, likes

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to inter life their septa here

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and has this sort of clustering area

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where some nodules are closer together, some portion

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of lungs are almost completely spared.

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So classic for perilymphatic, nodularity, all that together

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with the upper lung preponderance points straight

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to a diagnosis of sarcoidosis.

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Some people I think are confu get confused

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and say, oh, well you need

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to have associated lymphadenopathy.

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Remember, you don't need to necessarily need

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to see lymphadenopathy in someone

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who has pulmonary sarcoidosis, right?

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So the sarcoidosis can do what sarcoidosis wants,

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and sometimes there are essentially no lymph nodes at all,

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like in this case.

Report

Faculty

Jonathan H. Chung, MD

Professor of Radiology and Division Chief of Cardiothoracic Imaging

UCSD - University of California San Diego

Tags

Non-infectious Inflammatory

Lungs

Chest CT

Chest

CT