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<v ->We move on from our first crystal deposition disease

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to our second,

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calcium pyrophosphate dihydrate deposition disease.

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If you're going to abbreviate it,

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the proper abbreviation is not CPPD

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but CPPD deposition disease.

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I've listed here some of the terminology

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that you should remember.

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CPPD calcium pyrophosphate dihydrate

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is the abbreviation

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for the crystal that causes this disease.

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Pseudogout is one type of clinical presentation.

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It represents intermediate,

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intermittent rather acute attacks of arthritis

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simulating gout,

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but some patients with this disease

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have pseudorheumatoid arthritis.

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Some have pseudo-osteoarthritis, some indeed

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pseudoneuropathic disease but the vast majority

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of patients are asymptomatic.

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Chondrocalcinosis means cartilage calcification.

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Most common cause of widespread chondrocalcinosis

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is calcium pyrophosphate deposition.

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But other crystals including calcium hydroxyapatite

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can produce localized areas of chondrocalcinosis.

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Furthermore in CPPD deposition disease

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more than cartilage calcifize.

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So although you remember it most as meniscal

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in hyaline cartilage calcification perhaps about the knee,

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I'm gonna show you it's far more widespread than that.

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And then finally, pyrophosphate arthropathy.

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That refers to structural joint damage

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that has many similarities to osteoarthrosis,

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but differs in some classic ways.

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And the most important of those classic ways

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is a difference in distribution as I will show you.

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Also I would indicate calcium pyrophosphate dihydrate

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disease is the second most common

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articulate disease that I see.

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And the first being osteoporosis.

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So many of you hearing my voice right now

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will get this disease if you live to be elderly.

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Now that's the bad news. The good news is

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it's likely it won't produce significant symptomatology.

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I compare the deposition of pyrophosphate crystals now

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to the deposition of urate crystals.

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When we look at gouty crystals, they tend to occur

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on the surface of fibro cartilage and on the surface

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of Hyaline cartilage.

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This is called icing. And I think it's a term used

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when you study gout with ultrasonography.