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Training Collections
Library Memberships
On-demand course library with video lectures, expert case reviews, and more
Fellowship Certificate™ Programs
Practice-focused training programs designed to help you gain experience in a specific subspecialty area.
Ultimate Learning Pass
Unlock access to our full Course Library and all self-paced Fellowships.
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Complete all of your state CME requirements in one convenient place.
Noon Conference (Free)
Get access to free live lectures, every week, from top radiologists.
Case of the Week (Free)
Get a free weekly case delivered right to your inbox.
Case Crunch: Rapid Case Review (Free)
Register for free live board reviews.
Dr. Resnick's MSK Conference
Learn directly from the MSK Master himself.
Lower Extremities MRI Conference
Musculoskeletal Imaging
PET Imaging
Pediatric Imaging
For Training Programs
Supplement your training program with case-based learning for residents, registrars, fellows, and more.
For Private Practices
Upskill in high growth, advanced imaging areas.
Compliance
NewTrack, fulfill, and report on all your radiologists' credentialing and licensing requirements.
Emergency Call Prep
Prepare trainees to be on call for the emergency department with this specialized training series.
Lesson
Introduction to PET/CT Imaging
12 topics, 49 min.
Introduction to PET/CT Imaging
1 m.How to Use the Case Viewer to Evaluate PET/CT Images in this Course
2 m.What is PET/CT Imaging?
7 m.Commonly Used Positron-emitting Radionuclides
2 m.PET/CT Imaging Acquisition
4 m.PET/CT Quality Control
5 m.Quantification of Tracer Uptake
6 m.Factors Impacting Quantification of Tracer Uptake
3 m.Where to Start: Reading a PET/CT Study
9 m.Case: Systematic Approach to Reading a PET/CT Study
9 m.Case: Setting Up Your Imaging Display for a PET/CT Study
5 m.PET/CT Report Example
2 m.Lesson
FDG Use in PET/CT
8 topics, 28 min.
Introduction to FDG
4 m.FDG: Patient Preparation
2 m.FDG: Patterns of Muscle Uptake
6 m.FDG: Patterns of Bone Marrow Uptake and the Effects of G-CSF
5 m.FDG: Patterns of Bone Marrow Uptake and the Effects of Bone Marrow Disease
3 m.Case: Normal Distribution of FDG Tracer
4 m.Case: Abnormal Distribution of FDG (Hyperinsulinemia)
6 m.Cases: Abnormal Distribution of FDG (Hyperinsulinemia, Rhabdomyolysis, Myositis)
2 m.Lesson
FDG: Common Pitfalls and Benign Lesions
9 topics, 21 min.
Lesson
FDG Use in Hematologic Malignancies
8 topics, 40 min.
Role of FDG PET/CT Imaging in Lymphoma: Classification and Staging
7 m.Role of FDG PET/CT Imaging in Lymphoma: Response to Therapy
3 m.Role of FDG PET/CT Imaging in Lymphoma: Follow-up Reports
3 m.FDG Case: Hodgkin's Lymphoma, Initial Presentation
9 m.FDG Case: Hodgkin's Lymphoma, Follow-up
6 m.FDG Case: DLBCL, Initial Presentation
5 m.FDG Case: DLBCL, Follow-up
5 m.FDG Case: Multiple Myeloma
7 m.Lesson
FDG Use in Lung Cancer
5 topics, 17 min.
Lesson
FDG Use in Head & Neck Cancer
3 topics, 14 min.
Lesson
FDG Use in Breast Cancer
2 topics, 8 min.
Lesson
FDG Use in Immunotherapy
3 topics, 18 min.
Lesson
DOTATATE Use in PET/CT
7 topics, 15 min.
Lesson
DOTATATE and FDG Use in Neuroendocrine Tumors
6 topics, 22 min.
Lesson
PSMA Use in PET/CT
4 topics, 9 min.
Lesson
PSMA Use in Prostate Cancer
5 topics, 23 min.
0:00
Now we're gonna discuss briefly factors impacting your
0:04
quantification regarding the biologic factors.
0:07
These are most important on FDG PET CT
0:12
as we have seen in the SUV formula.
0:16
Things like body weight
0:17
and body size are, are going to be impactful
0:21
in our measurements.
0:24
The blood glucose level is also important
0:28
to have within a normal range because
0:31
otherwise the distribution of the tracer will be abnormal
0:34
and therefore the uptake in the lesion
0:37
of interest will also change.
0:40
And other things such as injection uptake time,
0:45
particularly differences in the uptake.
0:48
Time between comparisons is important to acknowledge
0:53
as they will change the SUV calculation.
0:57
Respiratory motion is also an important factor
1:00
that alters the calculation of the SUV values
1:06
because the target will be moving and
1:09
therefore the uptake recorded at each position will be
1:13
average and it could be lower
1:16
than it would if it was a static position.
1:21
There are medical technical factors that can also impact the
1:25
quantification and SUV values.
1:29
Uh, and this include the spatial resolution of your scanner,
1:32
time of flight, 2D versus a 3D system, the type
1:36
of reconstruction, the field of view, the metric size,
1:40
and many others.
1:42
And while this might seem very technical, it's important
1:46
to know what your scanner is,
1:49
particularly in those cases
1:52
in which a patient is being followed.
1:55
And you might be quantifying the activity of the tumor
2:00
before treatment and how this tumor has responded
2:04
after the treatment.
Factors Impacting Quantification of Tracer Uptake
HIDEInteractive Transcript
0:00
Now we're gonna discuss briefly factors impacting your
0:04
quantification regarding the biologic factors.
0:07
These are most important on FDG PET CT
0:12
as we have seen in the SUV formula.
0:16
Things like body weight
0:17
and body size are, are going to be impactful
0:21
in our measurements.
0:24
The blood glucose level is also important
0:28
to have within a normal range because
0:31
otherwise the distribution of the tracer will be abnormal
0:34
and therefore the uptake in the lesion
0:37
of interest will also change.
0:40
And other things such as injection uptake time,
0:45
particularly differences in the uptake.
0:48
Time between comparisons is important to acknowledge
0:53
as they will change the SUV calculation.
0:57
Respiratory motion is also an important factor
1:00
that alters the calculation of the SUV values
1:06
because the target will be moving and
1:09
therefore the uptake recorded at each position will be
1:13
average and it could be lower
1:16
than it would if it was a static position.
1:21
There are medical technical factors that can also impact the
1:25
quantification and SUV values.
1:29
Uh, and this include the spatial resolution of your scanner,
1:32
time of flight, 2D versus a 3D system, the type
1:36
of reconstruction, the field of view, the metric size,
1:40
and many others.
1:42
And while this might seem very technical, it's important
1:46
to know what your scanner is,
1:49
particularly in those cases
1:52
in which a patient is being followed.
1:55
And you might be quantifying the activity of the tumor
2:00
before treatment and how this tumor has responded
2:04
after the treatment.
Report
Faculty
Elisa Franquet Elia, MD
Assistant Professor of Radiology
UMass Chan Medical School
Tags
Response and assessment
PET/CT FDG
PET
Oncologic Imaging
Nuclear Medicine
Neoplastic
General Oncologic Imaging Concepts
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