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Wk 5, Case 5 - Review

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So this was a young patient, I think she was on 35 years old,

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that presented with hoarseness and strider.

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So when we look at the larynx,

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what we see is that up at the supraglottic larynx, it looks pretty, pretty good.

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The one thing that's a little concerning is that, you know,

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it's a little bit of dilatation, larygeal ventricles, but that can be normal.

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Once we get down to the true vocal cord, they look pretty well.

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But once we get down to the subglottic larynx,

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we can see there's marked narrowing of the subglottic larynx.

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And when we look at the bone algorithms, what we see here,

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so once we see the narrowing,

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we can see it's actually being caused by this mass right here,

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which is involving the crico cartilage.

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So this narrowing of the larynx is not due to a

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mucosal lesion involving the surface of the larynx,

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but rather it's due to a heterogeneous

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ossified or calcified mass that's originating from the crico

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cartilage. So when you see something like this,

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the diagnosis in the majority of cases is gonna be a chondro sarcoma

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involving the Crico cartilage. So in a way it's a bit of an ant many.

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So let me take any questions there if you, if, if you have any.

1:19

Oh, how they're treated. That's a really good question. Yeah,

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it's a really good question. So it really depends. Uh,

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these can be treated either with nothing and just watched,

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just based on the patient's clinical symptoms.

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I've seen some of those being followed. Um,

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I've also seen some of these being resected and if they do resected though,

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they're gonna have to do a total laryngectomy with, um, a sleeve resection.

1:46

Um, it's a good question.

1:48

I haven't seen that many that are being treated with radiation therapy. Um, uh,

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but I assume radiation therapy could be an option. In general,

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sarcomas don't respond well to radiation therapy. So what I've seen is either,

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uh, resection in order to maintain the integrity of the airway, um, or, um,

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just being followed to make sure they don't rapidly enlarge it. If they do,

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then they'll have to be treated with the total laryngectomy. Han,

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do you have any questions?

2:15

Uh, no. Is it very common?

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Uh, you know, it's always a question of what's common. Um, I would just say,

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I would say it's not necessarily uncommon. I think, uh, um, you know, you,

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you can, you can see these, is it as common as squamous cell carcinoma? Uh, not,

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no, no chance. Uh, but on the other hand, if you, if you look at these, um,

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sometimes you'll see the cartilage can be very interesting. Uh,

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oftentimes when we see these,

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you can see these little subtle abnormalities involving the thyroid cartilage,

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and we typically attribute it to end CDR Romas. So, um, but uh,

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yeah, you'll occasionally see these con sarcomas.

Report

Patient History
Hoarseness and stridor.

Findings
Contrast-enhanced CT was performed from the skull base to the thoracic inlet. The study demonstrates ill-defined mass involving the subglottic larynx that appears to be arising from the left half of the cricoid cartilage. This mass is expanding the cricoid cartilage and associated with a likely chondroid matrix. There is associated surrounding soft tissue mass that extends into the adjacent soft tissues. This mass subglottic larynx and extends from the undersurface of the true vocal cords to approximately the 1st tracheal ring. The superior aspect of the mass involves the undersurface of the left true vocal cord resulting in mild left medialization of the cord.

No evidence of aggressive lesions is identified in the nasopharynx, oral cavity, or hypopharynx. No evidence of enlarged lymph nodes using standard size criteria.

Visualized portion of the brain is grossly within normal limits. However, dedicated brain imaging is necessary for complete diagnostic evaluation.

Visualized portion of the lungs appears to be within normal limits. However, dedicated chest CT is necessary for complete diagnostic evaluation.

Conclusions
1. Subglottic mass arising from the left half of the cricoid cartilage that appears to have a chondroid matrix with associated soft tissue mass resulting in narrowing of the subglottic larynx. Findings are most consistent with a chondrosarcoma of the cricoid cartilage.

Case Discussion

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Suresh K Mukherji, MD, FACR, MBA

Clinical Professor, University of Illinois & Rutgers University. Faculty, Michigan State University. Director Head & Neck Radiology, ProScan Imaging

Tags

Neuroradiology

Head and Neck

CT