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0:00
This was an example of a two year old that ended up having an intraocular
0:05
mass and then also had multiple lesions involving the brain. I think I,
0:10
I think you, did you think that this was a neurofibromatosis?
0:13
Is that what you thought? Was that you or somebody else?
0:17
Somebody else.
0:18
Somebody else. Okay. Did you get the diagnosis here? Yes. Of retinoblastoma.
0:23
Okay. Very good. Yeah. So in a two-year-old, when you see something like this,
0:27
see the Corona, and you see all this, these masses that are intraocular,
0:31
then the most likely diagnosis in a patient with leukocoria is gonna be, um,
0:36
retinalblastoma. And the interesting thing about this case, unfortunately,
0:40
is that the retinoblastoma extended posteriorly to the globe and grew back along
0:45
the optic nerve and all the way back here into the, um, cell.
0:50
So the terminology we sort of used to use was a trilateral
0:55
retinoblastoma. That's what we used to refer to it.
0:59
But I think in actuality what it is,
1:01
it's just basically intracranial metastases of retinalblastoma.
1:05
The other things here, you can see a little bit of abnormal enhancement here.
1:10
Um, you can see the abnormal enhancement, uh,
1:13
probably in the internal auditory canal.
1:15
See this area here and here can zoom that up a little bit.
1:20
So here and here, and what was kind of unfortunate, um, in this case,
1:26
but if you like anatomy, it was, it was kind of interesting,
1:29
is that if you mag this up,
1:33
here is the bows or artery. Here is the posterior cerebral artery.
1:36
Here's the superior cerebellar artery. You can see this mass right here.
1:40
What nerve do you think that's involving? That's, uh,
1:44
going between the P C A and the S C A,
1:48
Uh, that mass.
1:49
Beautiful. Exactly right.
1:50
So this was a metastases actually involving the third nerve. Mm-hmm.
Interactive Transcript
0:00
This was an example of a two year old that ended up having an intraocular
0:05
mass and then also had multiple lesions involving the brain. I think I,
0:10
I think you, did you think that this was a neurofibromatosis?
0:13
Is that what you thought? Was that you or somebody else?
0:17
Somebody else.
0:18
Somebody else. Okay. Did you get the diagnosis here? Yes. Of retinoblastoma.
0:23
Okay. Very good. Yeah. So in a two-year-old, when you see something like this,
0:27
see the Corona, and you see all this, these masses that are intraocular,
0:31
then the most likely diagnosis in a patient with leukocoria is gonna be, um,
0:36
retinalblastoma. And the interesting thing about this case, unfortunately,
0:40
is that the retinoblastoma extended posteriorly to the globe and grew back along
0:45
the optic nerve and all the way back here into the, um, cell.
0:50
So the terminology we sort of used to use was a trilateral
0:55
retinoblastoma. That's what we used to refer to it.
0:59
But I think in actuality what it is,
1:01
it's just basically intracranial metastases of retinalblastoma.
1:05
The other things here, you can see a little bit of abnormal enhancement here.
1:10
Um, you can see the abnormal enhancement, uh,
1:13
probably in the internal auditory canal.
1:15
See this area here and here can zoom that up a little bit.
1:20
So here and here, and what was kind of unfortunate, um, in this case,
1:26
but if you like anatomy, it was, it was kind of interesting,
1:29
is that if you mag this up,
1:33
here is the bows or artery. Here is the posterior cerebral artery.
1:36
Here's the superior cerebellar artery. You can see this mass right here.
1:40
What nerve do you think that's involving? That's, uh,
1:44
going between the P C A and the S C A,
1:48
Uh, that mass.
1:49
Beautiful. Exactly right.
1:50
So this was a metastases actually involving the third nerve. Mm-hmm.
Report
Patient History
2-year-old with left leukocoria.
Findings
Contrast-enhanced CT was performed from the skull base to the thoracic inlet. The study demonstrates a large calcified left intra-ocular mass which is slightly enlarging the left globe. The mass has both a soft tissue and calcified component. The left lens is not visualized and may be eroded by the intra-ocular mass.
There is diffuse enlargement of the left optic nerve extending posteriorly through the left superior orbital fissure and optic canal. There is enlargement of the orbital apex, left superior orbital fissure and left optic canal indicative of a longstanding process. The coronal images demonstrate lateral displacement of the supraclinoid carotid artery suggestive of a sellar/suprasellar mass and can be further evaluated with contrast-enhanced MRI of the brain.
No evidence of enlarged lymph nodes are identified. The right globe appears to be within normal limits without evidence of calcified intra-ocular mass.
Visualized portion of the lungs is grossly within normal limits. However, dedicated chest CT is necessary for complete diagnostic evaluation.
Conclusions
1. Large calcified intra-ocular mass consistent with retinoblastoma.
2. Diffuse enlargement of the left optic nerve likely due to retrobulbar involvement with extension along the left optic nerve.
3. Findings suggestive of a sellar/suprasellar mass which may represent intracranial extension/metastases.
Case Discussion
Faculty
David M Yousem, MD, MBA
Professor of Radiology, Vice Chairman and Associate Dean
Johns Hopkins University
Suresh K Mukherji, MD, FACR, MBA
Clinical Professor, University of Illinois & Rutgers University. Faculty, Michigan State University. Director Head & Neck Radiology, ProScan Imaging
Tags
Neuroradiology
MRI
Head and Neck
CT
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