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Wk 10, Case 1 - Review

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0:05

So this was a pace that presents with a mass right here involving the right

0:09

protic gland.

0:10

The thing about this mass is I think some people ended up saying an abscess,

0:14

which is reasonable, but the patient was, um, essentially afebrile.

0:19

So they didn't have any signs and symptoms of inflammatory processes or, or,

0:24

or an infectious process.

0:26

So if you do see a cystic mass like this involving the parotid gland,

0:31

especially in the us so granted,

0:33

if I was in India and I saw something like this and maybe in,

0:37

maybe in Malaysia too,

0:38

then you'd have to think of some type of endemic infections,

0:41

like maybe neuro cystic psychosis. But in general,

0:44

it's kind of rare to have a single isolated cyst like this.

0:47

But the most common congenital lesion that you end up seeing in the

0:52

parot gland in a child is gonna be a first brachial anomaly.

0:57

So I did bring this up.

1:00

So the brachial anomalies is that basically they arise from the brachial

1:05

arches. So you know, there's the first brachial um, arch,

1:09

the second brachial arch, et cetera.

1:11

So the first brachial groove gives rise to the external

1:16

auditory canal. So when you're actually looking at the embryo right here,

1:20

this is the first arch and this is the second arch.

1:22

So this area right here ends up forming the external auditory canal.

1:28

So this is again,

1:29

a schematic illustration of the formation of the external

1:33

auditory canal is here, the middle ear Kathy is here,

1:39

and where this just move this, get it outta my way. Um,

1:44

where the

1:46

couch and the external auditory, uh,

1:50

groove form ends up forming the tympanic membrane.

1:54

So what the first brachial arches is that it is,

1:58

there are two types. There's a type one and there's a type two.

2:02

So the type one,

2:04

they're both felt to be duplications of the first brachial apparatus.

2:09

And a type one is basically an intracarotid cyst.

2:13

And we'll see the type two later.

2:15

This is a small little fistula that forms at the junction of the ex,

2:19

the external laboratory canal at the members and the bony junction.

2:23

And it forms a little fistula right here that extends all the way down and

2:28

typically into the region of the submandibular space. So again,

2:31

these are examples of type one first brachial anomalies.

2:34

You can see basically there's cysts right here.

2:37

So if we go back and then look at this case,

2:41

what we see here is the cyst that's involving the parotid gland in an afebrile

2:45

patient. And that turns out to be a first brachial cleft cyst.

2:50

Um, such this should say a type one first brachial anomaly.

2:54

Now what I did wanna say is that, you know, if you do see pure cyst in adult,

2:59

what I have noticed is that if this ends up,

3:03

let's just say this never presented in the child,

3:05

but it ends up presenting an adult,

3:07

then this could be due to quote unquote a parotid cyst.

3:10

It could be due to a unilateral um, salal. But, um,

3:15

years ago we did this study where we actually correlated, um,

3:20

pathology with first brachial anomalies, excuse me,

3:23

I should say congenital anomalies. And what we found out in adults,

3:27

a certain percentage of these that present with these asymmetric a asymptomatic

3:32

intra paric cysts are actually type one first brachial anomalies.

3:37

So let me stop there and then you can ask any questions you want to on this.

3:42

So in, uh, in it still can be the first anomaly.

3:47

Yes, yes. Type one first anoma. Exactly right.

3:50

So there has to be at least included in the differential diagnosis for purely

3:56

cystic lesions for purely cystic,

3:57

Not only the cystic. Yes. Not only the cystic metastatic lymph node.

4:02

For oral pharyngeal ca

4:04

Uh, it would be unusual to have a inid cystic lymph node

4:10

for oral pharynx.

4:10

So that cystic mass was in an adult in a level two lymph node

4:15

that a hundred percent that then you'd have to consider that. Okay.

4:19

The fact that it's actually within the parotid gland. And that makes, um,

4:22

it very unusual.

4:24

This one initially I thought is a part of the says.

4:28

Mm-hmm. Yeah, yeah. Which is reasonable, which is, I remember I saw your report,

4:32

I think that was very reasonable.

4:34

But I think in the comments when I graded your report, I think I said, well,

4:37

the only thing is that there was no history of it.

4:41

'cause I very rare to see type one brain Q anomaly because 80% will be type

4:46

two.

4:47

No, just the opposite 80% are gonna, well, no, hold on for a second. Now.

4:50

So realize,

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I mean the, for the type two brachial anomaly,

4:55

not the type two first al anomaly,

4:59

Right? I think so just to clear up the, the, the, the, your lexicon,

5:04

there's first brachial anomalies in which

5:07

Or second Yes.

5:07

Type one and type two first, brachial anoma,

5:09

then there's second brachial anomalies.

5:11

And I think what you're saying is that the most common brain anomaly second is a

5:15

second, right? That's correct. That's exactly right. Very good.

5:19

Because for the second itself, there are four types.

5:23

Yes, that's exactly right.

5:24

Con confusing. Yes,

5:26

Exactly right. How did you learn that? Did I, did you, do you remember? I,

5:29

'cause I

5:29

Saw most of,

5:30

I think I saw most of the patient with the second er

5:36

and normally I seen the sinus fistula,

5:40

different types of second er. Yeah. And normally in my practice,

5:44

Yeah. Oh, that's good. Do you see this, do you see the diagram here?

5:47

So this is the four types of second brachial anomalies.

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So you have one,

5:53

the type ones are typically involving the skin and the platysma muscle.

5:57

So this is path proven type one second.

6:00

This was the classic type two second.

6:02

So when you look at the second brachi anomalies,

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the type two is the most common.

6:06

The type three extends between the internal and the external carotid artery,

6:09

and it actually visualizes to the tonsil. So for me,

6:13

the way I remember this is that if they actually do a fistulagram and you see

6:17

the fistula extending all the way to the tonsils,

6:21

and then it's going between the internal and the external carotid artery,

6:24

then that's a type three.

6:25

And the type fours are located deep to the plane of the internal and the

6:29

external carotid artery. So again, it's a little bit more common than,

6:32

than you would expect. So I think a lot of these are sometimes referred to,

6:37

or they may be misclassified as these a para pharyngeal cyst or

6:42

a,

6:43

a consular cyst or a cystic retropharyngeal mass.

6:48

But, uh, just in the back of your mind,

6:50

you have to realize if it's purely cystic and the patient's asymptomatic,

6:55

it actually could be a type four brachial cleft, uh,

6:58

a type four brachial arch anomaly. In fact,

7:01

there was a case about 15 years ago where we saw this and I thought it was gonna

7:06

be like a cystic parotid lymph node, but one of my colleagues say,

7:08

could it be a type four second? And it turned out it was a type four second. So,

7:13

uh, just realized if you have these pure cyst, you know, in,

7:15

in addition to a tonsor cyst, it could be a type four brachial, uh,

7:20

type four second brachial cleft cyst.

7:24

And you might, uh, show us the third and four,

7:28

because it's very hard to differentiate between the two. Yep,

7:31

Sure can. It's actually, you know, it's not that hard. Um,

7:35

and I'll tell you why. Okay. So, so you got the, we'll,

7:40

we'll go over the first, right? So we talked about type one first,

7:43

and I think another case is gonna be at type two first. You got that right?

7:47

Mm-hmm. And then we talked about the second,

7:50

which is predominantly involving the tonsil, right? So you got this here.

7:53

Mm-hmm. The type three are actually more common than you think they are.

7:57

So the type three is associated with the piriform sinus,

8:01

and then it crosses between, um, it,

8:04

it actually crosses posterior to the internal, uh,

8:07

carotid artery and runs between the ninth and the 12th nerve.

8:11

But the key thing here is that it's located in the posterior triangle.

8:16

So the,

8:17

the one here on the left was actually pathologically proven third brachial

8:21

anomaly. It was a third brachial cyst and they,

8:23

they took it out 'cause I thought it was gonna be a metastatic lymph node,

8:26

but this was actually a pathologically proven third brachial anomaly.

8:31

And then the more common appearance is that if you have this little cystic mass

8:34

that's located in the posterior triangle,

8:36

this was actually a pathologically proven third brachial anomaly.

8:40

So the way to think the thirds is that if you see a cyst right here,

8:45

that's tic lesion, that's actually posterior to the,

8:49

the external carotid artery. You know, the number one that you,

8:52

that you think about is gonna be a lymphatic malformation,

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but it is the second most common lesion to involve the posterior triangle.

8:59

So that's the way the third is.

9:03

And the other thing for the third, uh, oh yeah, that's, that's the third.

9:05

So the next one is gonna be the fourth. Now I have to admit, I've seen,

9:11

I have seen a lot of confusion as to what's the, what's a third and a fourth.

9:16

The way that I look at it is that I know that the fourth starts

9:21

at here, at the piriform of sinus, goes up and then comes down, okay,

9:25

that's the embryology of the third.

9:28

The fourth is actually pulled down.

9:31

It's actually tethered down down.

9:34

So the fourth can also pierce a thyroid hyoid membrane.

9:37

And there's some controversy as to the difference be where the fistula is gonna

9:42

be, be between the third and the fourth.

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But in general the fourth is right at the apex. So if it's at the apex,

9:48

they tend to extend more inferiorly.

9:52

So this was a patient of a fourth brachial anomaly because it was involved in

9:56

the apex. And notice,

9:57

here's the piriform sitis here and see this little lesion extending down

10:02

inferiorly.

10:02

And these are the ones that typically present with recurrent thyroiditis or

10:06

recurrent anterior neck masses. And then they can,

10:10

they can continue to extend all the way down into the mediastinum.

10:14

So one more example here. This is the, uh, type one first.

10:19

So this is actually in the Prada gland.

10:22

This is a type two first because we can see this area extending here into the

10:25

extra laboratory canal. These are the four types of second.

10:30

So that's involving the skin. This is the classic type two second,

10:34

this is the type three third, and then this is the type four, uh, excuse me,

10:39

type three second. And this is the type four second path proven here.

10:42

And then this is an example of a third bronchial anomaly.

10:46

Notice how it's involving the posterior triangle and then here's an example of a

10:51

fourth brachial anomaly.

10:53

And notice how it's involving the piriform sinus and presenting with recurrent

10:57

anterior neck masses. So those, the way that I classify them, and I think it's,

11:01

I think that's what most people do. Does that answer your question?

11:06

Yeah, it's very clear explanation. Okay, good. Excellent.

11:11

I think a few days ago I saw a patient with the, looked like a four,

11:15

four ular anomaly with the abscess in near the visitor space.

11:20

It's very unusual. Mm-hmm. Without any foreign body injection.

11:25

Maybe that kind of patient may, may have the foot Brinker anomaly. Right.

11:30

Was it a child or an adult?

11:32

Oh, it's an adult.

11:33

Adult, okay.

11:34

Any uhhuh?

11:36

Yeah, no. Be, um, you know,

11:38

one thing you can do if you're wor if you're concerned about is make sure you do

11:41

the reconstructions. Because sometimes you may not be able to see on the axials,

11:45

but if you did have anterior neck infections, make sure you look at the,

11:49

the coronals. I had a case of that too actually recently,

11:53

and I was sort of raised the possibility of a fourth as well.

11:57

So what,

11:57

so I look in the Corona to look at any communication with the apex or the

12:02

sinus?

12:03

Yeah. Just in case. Sometimes if you look real closely,

12:05

you'll see a little air pocket. If you see something like that,

12:07

that make sure you do your reconstructions.

Report

Patient History
Afebrile 6-year-old male with right cheek mass within intact facial nerve.
Findings
Contrast-enhanced CT was performed from the skull base to the thoracic inlet. Study shows no evidence of aggressive lesions involving the nasopharynx, oral cavity, tongue base, tonsils, larynx or hypopharynx. No evidence of enlarged lymph nodes using standard size criteria.

There is an approximately 1.9 cm x 1.6 cm (axial dimensions) cystic mass involving the right parotid gland. The mass involves the midportion of the right parotid gland and extends superiorly to the junction of the membranous and bony external auditory canal. A component of the mass extends superiorly deep to the pinna and abuts the outer margin of the mastoid air cells. Bone algorithm suggests possible regressive remodeling involving the superolateral bony wall of the external auditory canal. The majority of the mass is intraparotid and involves both the superficial and deep lobe. There is no evidence of extension of the mass to the skin which would suggest a sinus.

Visualized portion of the brain is grossly within normal limits. However, dedicated brain imaging is necessary for complete diagnostic evaluation.

Visualized portion of the lungs is grossly within normal limits. However, dedicated chest CT is necessary for complete diagnostic evaluation.

Conclusions
Approximately 1.9 cm x 1.6 cm cystic mass involving the right parotid gland that extends superiorly and abuts the bony cartilaginous junction of the external auditory canal. In an afebrile patient within intact facial nerve, these findings are most consistent with a type 1 first branchial anomaly.

Case Discussion

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Suresh K Mukherji, MD, FACR, MBA

Clinical Professor, University of Illinois & Rutgers University. Faculty, Michigan State University. Director Head & Neck Radiology, ProScan Imaging

Tags

Neuroradiology

Head and Neck

CT