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Wk 2, Case 1 - Review

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Okay, so this was the first case of a right neck mass.

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So what I've got up is the T one weighted scan and the stir T two Wade scan

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and stir, because there's inversion recovery and good fat suppression. Um,

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I like looking at the T one weighted scans to define the anatomy because you

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have the bright fat that helps you in the head and neck.

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Um, and then the, the stir helps identify the pathology.

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So if we initially look at the stir images and we start at the, at the top,

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in almost all situations in the head neck,

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the pathology's gonna be bright because the muscles are very, very dark.

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So if you look at the mass term muscle and the OID muscle, it's very dark. So,

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and the tongue muscle.

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So usually the things that are brighter are the things that are the pathology.

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And here we see a mass that is on the right side,

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and it looks like it's in the floor of the mouth.

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The floor of the mouth is synonymous with the sublingual space,

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and it includes the sublingual gland as well as all the mucosa there.

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So if we look on the contralateral side, we see the sublingual glandular tissue,

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which is this gray stuff.

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And on either side of the sublingual grandular tissue, we have muscle.

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The muscle that's lateral to it is the mylohyoid muscle.

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And the muscle that's medial to it is the stylos is hilos, is complex.

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The stylos is obviously going from the sty process to the tongue,

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and then it intertwines with the hilos,

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which goes from the tongue to the hyoid bone. So on the contralateral side,

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here's our mylohyoid muscle. Here's the lesion. It's in the sublingual space.

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Here's the other muscle.

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The muscle on either side here is the genial gloss muscle,

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which is the main muscle of the, uh, extrinsic muscle of the tongue.

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And this is the intrinsic musculature of the tongue.

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So we have a for of mouth mass,

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and it looks like it's projecting inferiorly along that

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sublingual space. And then, uh, continuing downward,

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we come into this large conglomerate of something that is

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lateral to the carotid sheath.

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And when we have a lesion in the mucosal space and a lesion

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outside in the neck, more likely than not, we're dealing with a cancer with a,

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um, with a lymph node. So on the t one way scan, again,

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we can see the anatomy pretty nicely, the mylohyoid being displaced laterally.

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Here's again, our sublingual glandular tissue,

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our stylo Hilo complex.

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This point's pretty much high glosses the displacement of the genial glos muscle

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on either side.

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And then we get a better sense of the irregularity of this mass as it

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infiltrates into the sty, uh,

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Sternal clid mastoid muscle lateral to the carotid sheath.

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So, um, on the post contrast scan,

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we can see the kind of speculated edge to this, uh,

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nodal mass, um,

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and how it's infiltrating the sternal CID mastoid muscle.

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And that would imply extra nodal extension. Um,

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extra nodal extension is sort of a pathologic term,

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but it does, um, it, it,

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we do have imaging findings that correlate well with the pathology.

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So primary tumor

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with nodal metastasis. And on the stir,

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we also, incidentally, when we went down lower, we, uh,

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saw some thyroid nodules, which, you know,

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are pretty common in humans. And,

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um, here we're getting a little bit of the bright signal of the, uh,

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brachial plexus. And I think that Dr.

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Mukerjee will be talking to you about the brachial plexus shortly. Um,

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if we go down here, it,

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it's really vessels and brachial plexus more than anything.

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So we're looking at all the bright stuff.

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Basically what we're not seeing is contralateral enlarged lymph nodes,

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which is a pertinent negative.

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So we have little small lymph nodes that are less than a centimeter,

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so we don't, uh, necessarily have to call that.

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So with regard to the primary tumor,

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far and away primary tumors in the aero digestive system,

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we're gonna be squamous cell carcinomas.

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That's what should be number one in this location where you do have

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sublingual glandular tissue, you might think, uh,

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in your differential diagnosis of a salivary gland neoplasm,

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but you'd have to go with an a malignancy because we have a nodal metastasis.

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So yeah, it could potentially be also in,

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we could consider lymphoma. That's usually not in this location,

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but more in the ER's ring of the nasal pharynx, adenoids,

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the palatine tonsils, and lingual tonsor tissue. So, um,

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we wanna measure this lesion because that will help with the T staging.

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So this is the, uh, t staging for oral cavity cancers.

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The floor of the mouth is considered an, uh, location of the oral cavity,

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not the oral pharynx, but the oral cavity.

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And therefore we have to measure the size of the lesion.

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This depth of invasion is how deep it's going from the

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mucosal surface. Again, although this is a pathologic definition,

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we can usually make some statements about by looking at the lesion,

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usually in a superior inferior dimension on the tongue or in the

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floor of mouth. Again, superior inferior to see how far deep it's going, and

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Make some estimation. Uh, two to four centimeters

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or five to 10 depth of invasion greater than four

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centimeters. This was in the two to four centimeter range. So T two.

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And then does it invade cortical bone, maxillary sinus,

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or does it get into the masticator space musculature, the OID plate,

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the skull base, or the internal car artery? So we don't have any of those.

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For the nodal staging, it's usually three to six centimeters,

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three centimeters or less, or T one, if it's bilateral, uh,

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lymph nodes, it would be T two B, if it's con, uh,

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if it's, um, greater than three to six, if it's in the three to six centimeters,

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also T two cancer. And then we have these issues about extra nodal extension.

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In this case, if there is extra nodal extension, let me, uh,

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pull up the nodal staging. So, uh,

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ipsilateral three centimeters to a three,

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three less than three centimeters. Um,

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two B multiple,

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two C bilateral contralateral.

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So single node and, um, multiple nodes,

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and then nodes greater than six centimeters, three A,

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and then if you have extra nodal extension, it bumps it up to three B.

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So in this case, we have a extra nodal extension. So that,

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uh, makes it a higher grade lesion. Here again, pathologically,

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extra nodal extension, negative versus positive, et cetera.

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So as far as the thyroid gland goes,

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almost all of us have a macro,

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which refers to the a c r guidelines on thyroid nodules,

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depending upon whether the patient's 35 years of age or more.

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And those guidelines say that you don't have to pursue with an ultrasound if

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you're less than 35 years old and the node is less than one centimeter

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inside. But if it's greater than one centimeter in sizing, you're 35 years or,

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or more, you, you re you have to, you should recommend an ultrasound.

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So there's a macro that we all put into when we see these, uh, thyroid nodules.

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In a lot of ways the clinicians would prefer, we just don't even mention them.

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But there you go.

Report

Patient History
Right neck mass.

Findings
Pre and postcontrast MR was performed from the skull base to the thoracic inlet. The study demonstrates an approximately 2 cm x 1.5 cm mass involving the anterior floor mouth. The mass medially displaces the ipsilateral genioglossus-geniohyoid complex and laterally displaces the right mylohyoid muscle. The posterior aspect of the mass extends to the anterior tongue base. However the mass is contained within the right sublingual space without evidence of tongue base invasion. The mass is high signal on T2, low signal on T1 and homogeneously enhances with contrast.

There is a large right level 2 nodal metastases which extends inferiorly to involve the superior portion of level 3. The mass anteriorly displaces the posterior aspect of the right submandibular gland. The nodal mass contains focal areas of increased T2 signal which is likely due to necrosis. The margins of the nodal mass are ill-defined and abuts the anteromedial portion of the right sternocleidomastoid muscle. In addition, there is enlargement the right sternocleidomastoid muscle. These findings are suggestive of imaging evidence of extra capsular penetration with fixation to the sternocleidomastoid muscle.

There is a 6 mm lymph node located in level 1B on the right. Although this is not larger than accepted size criteria, it is suspicious given that it is in a primary echelon drainage for a right for mouth carcinoma

There are multiple small lesions involving the thyroid gland the largest of which measures approximately 1 cm.

Conclusions
1. Approximately 2 cm x 1.5 cm oval mass involving right 4 mouth with ipsilateral nodal metastases with imaging findings suggestive of extra capsular penetration. Findings are consistent with squamous cell carcinoma involving the right floor of mouth.
2. Multiple thyroid nodules the largest of which is approximately 1 cm. Would refer to appropriate TI-RADS criteria for further management decisions.

Case Discussion

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Suresh K Mukherji, MD, FACR, MBA

Clinical Professor, University of Illinois & Rutgers University. Faculty, Michigan State University. Director Head & Neck Radiology, ProScan Imaging

Tags

Neuroradiology

MRI

Head and Neck