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Wk 3, Case 2 - Review

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This was a patient with clinical findings suggestive of left trigeminal

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schwannoma with brainstem compression.

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Resh kind of threw a curve ball at you because this ends up not

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being a schwannoma. Um, and we'll try to explain why.

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So we're gonna look at this case again with our, our CYS imaging and, um,

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we'll do the same as what we did before. And that is to identify the,

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you know, the nerves down low,

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and that's such a great demonstration of the hypo hypoglossal nerve going

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into the hypoglossal canal there. Um,

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the nine 10 complex going towards the jugular

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foramen on either side. Um,

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here we come to the internal auditory canal,

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and on the normal right side,

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we can see multiple nerves entering the internal auditory canal.

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On the affected side, the left side,

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we see that the mass demonstrated here as this kind of iso

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intense tissue is displacing

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the seventh, eighth nerve complex posteriorly.

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And the mass does just enter the porous acoustics here

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on the, uh, left side.

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As we move further superiorly,

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we see the trigeminal nerve on the right side coming into Mecca's cave.

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On the left side, we honestly don't see the,

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the fifth cranial nerve. Here's Meles Cave.

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It's markedly enlarged compared to the normal Meles cave.

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And so it's filled with the mass.

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Here you can see the dural reflection being displaced

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laterally by the soft tissue in Mekel Cave.

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As we proceed more superiorly,

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we see that this lesion is on both sides of the

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tentorium. There's a component that's in the middle cranial fossa,

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and we, we see that, that it,

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it extends up further superiorly here.

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And what we're looking for

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is the third cranial nerve. And here we,

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we know that the third cranial nerve comes off between the

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posterior cerebral artery and the superior cerebellar artery.

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And so on the right side we see third cranial nerve coming from

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the intraocular cistern across and into

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cavernous sinus. On the affected side, we

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Have have the third cranial nerve here from the intraocular cistern coming

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across. And here's where the third cranial nerve abuts

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the mass as it enters the cavernous sinus.

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So there's contact with the third cranial nerve right here,

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right?

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So intraocular cistern coming across tumor against the third cranial nerve

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and then into the camera of sinus.

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So quite often the issue is not so much the histology of

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the mass as it is the, um,

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the important anatomy that you should be describing. We,

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we talk about the nerves, the arteries, and the bones. So in this case,

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you know, we've got portions of the, um,

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the vasculature here. We have the vass or artery, and

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we wanna talk about whether we see any vessels that are in close

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approximation to the, to the mass.

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You can see superior cerebellar artery being displaced immediately by the mass.

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So let's look at the post gadolinium enhanced images. Alright,

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so here's our mass. And, um, how,

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why would we say that this lesion is a meningioma,

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which was the correct histologic diagnosis as opposed to a,

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uh, fifth cornal nerve schwannoma? Well,

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the shape of this lesion is more in keeping with a meningioma in that it's along

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the plane of the dura rather than along the plane of the, um,

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fifth cranial nerve, which would be more AP oriented,

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if you will. We do have a little bit of a dural tail. It's not dramatic.

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Um, the, the,

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the lesion crossing the tentorium is another argument.

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Uh, fifth cran nerve schwannomas would not be up this high at the level of the

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midbrain.

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And this growth in into the middle cranial fossa, uh,

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argues against it being a schwannoma. Um, it is,

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as you saw on the stir, relatively iso intense.

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Here's our traditional T two A image,

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and then that's true with some schwans. They may also be, uh, iso intense.

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What we'd also look at would be to look for any bony reaction.

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So along the petrus bone,

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we would look for any type of reaction.

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You can see the way this is extending here is more in keeping

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with a meningioma.

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Let's on the coronal and see whether there's a better demonstration on

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dural tails or not. Yeah, this,

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This kind of dural enhancement might be a good argument for

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this. And notice the,

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the vascular involvement here as we, uh,

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see the posterior cerebral artery. So,

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um, in this case,

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the correct diagnosis was meningioma,

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and what you saw with regard to the commentary was

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a request to make note of the cranial nerves that were

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involved by the meningioma in order to elevate your score to the

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exceeds expectations. Um,

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one person, uh,

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was a pointed out the fact that there was a second meningioma,

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so that person also got exceeds expectation. Two,

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meningiomas do not make neurofibromatosis. Type two,

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you have to have a single, uh,

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in vestibular schwannoma plus a meningioma,

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multiple meningiomas to, to make the criteria for NF two. But, um,

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that was a nice pickup for somebody on the, uh, coronal image.

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And this is a, actually a pretty nice review article,

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not in a radiology journal, but the person did a good job.

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This is from the NH N I H trust. And, um,

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in this she reviews the, the anatomy of the, you know, the,

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the ninth 10 complex, the CP angle,

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and the seventh eighth nerve complex. And, um,

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you could see the anatomy on the cyst image again.

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And then she starts looking at different pathology that can

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occur in the cerebellum pontine angle. And, uh, does a pretty good job with, um,

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Vista Omas as well as

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some, uh, example of a facial nerve, Hema Angio,

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which is this little bubbly lesion at the icic ganglion.

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And then epidermoid cyst, which we will look at in just a moment.

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This is still the cranial nerve here,

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ninth, 10th nerve schwannoma,

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which is in our differential with vestibular schwannomas as well as potentially

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with our gloma tumors here. Um,

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meningioma with the base along the, uh,

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posterior fossa and with a little bit of a duro tail here is, uh,

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a case that showed restricted diffusion and looked kind of dirty

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cyst like, and this ended up being our epidermoid. This was an arachnoid cyst,

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uh, lesion. And then, uh, some lipomas,

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which are relatively unusual cases. So, um,

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look over this article.

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It seems like it's got nice illustrations of the different pathology

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in this, uh, part of the anatomy.

Report

Patient History
Clinical findings suggesting of left trigeminal schwannoma with brainstem compression.

Findings
Pre- and postcontrast MR was performed of the brain and skull base.

Brain: Sagittal images show the corpus callosum to be intact. No abnormal pineal region masses are seen. The pituitary gland is not enlarged. There is no evidence of Chiari malformation. Diffusion imaging shows no evidence of recent infarct. Susceptibility weighted imaging shows no evidence of hemosiderin staining. The axial FLAIR and T2 weighted images show some prominence of the sulci and ventricles. There is no evidence of obstructive hydrocephalus.

Skull base: The study demonstrates an approximately 3.3cm x 2.5cm homogeneously enhancing extra-axial mass located in the left cerebellopontine angle region. The posterior aspect of this mass extends to the porus acusticus with a very small component extending into the medial aspect of the internal auditory canal. The anterior aspect of this mass extends into the lateral aspect of the left prepontine cistern and continues anteriorly through Meckel's cave with complete involvement of Meckel's cave. There is no direct extension into the cavernous sinus, however, there is some mild effacement of the lateral wall of the left cavernous sinus. Left cranial nerves 3 and 6 are visualized in the left cavernous sinus. The superior aspect of the mass extends into the left perimesencephalic cistern. The inferior aspect of the mass extends along the dorsal aspect of the clivus to the level of the transverse segments of the petrous portion of the carotid arteries. The mass medially displaces the left middle cerebellar peduncle. There is partial effacement of the left 4th ventricle. However, there is no evidence of ventriculomegaly of the lateral or 3rd ventricle. The mass involves the expected location of the cisternal portions of left cranial nerves 5, 6, 7 and 8.

Conclusions
1. A 3.3 x 2.5cm homogeneously enhancing extra-axial mass located in the left cerebellopontine angle region and extends anteriorly into left Meckel's cave. The findings are most consistent with a meningioma.
2. Mass effect on the left middle cerebellar peduncle with mild partial effacement of the 4th ventricle. No evidence of obstructive hydrocephalus of the lateral ventricles.
3. No evidence of recent infarct.

Case Discussion

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Suresh K Mukherji, MD, FACR, MBA

Clinical Professor, University of Illinois & Rutgers University. Faculty, Michigan State University. Director Head & Neck Radiology, ProScan Imaging

Tags

Neuroradiology

MRI

Head and Neck