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Cystic Adventitial Disease

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A less common disease of the artery

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that we encounter is the cystic advent disease.

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I have very little experience with this.

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Um, this is an old case, uh,

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from Scripps Hospital when we used to work there

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of bilateral cystic adventitial disease in a patient

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that had, uh, symptomatic claudication, uh,

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in a 30-year-old, uh, female.

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But, you know, honestly, I don't know

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how these are getting diagnosed because I look at this area

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and I see this, uh, very, very, uh, rarely.

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I'll show you a couple of examples.

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Uh, this is another patient,

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and again, it's, uh, the cystic collection.

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It was intimate with the vessel.

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Uh, but you can see this nice correlative angiogram.

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This is an older case again,

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where they did conventional angiography,

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and it's showing you the simar sign, uh,

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where the vessel is narrowed, uh, related, uh, to these,

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um, to these cysts.

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So these tend to be generally seen in younger males.

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They can be bilateral,

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and the most common site of this is the popliteal artery.

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Here we see another example, a more recent case.

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This patient was a bit older,

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and we have this very complicated cystic collection

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that's intimate, uh, with the, a popliteal artery.

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You can see it's being deviated.

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You can understand how this could produce that Simar sign,

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which is really characteristic of this.

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But what I think is really interesting is

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what we've been learning more recently from work by spinner

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who has done a lot of articles on perineural, uh,

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ganglia and has written a lot about ganglia at the proximal

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tibial fibular joint.

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And he believes that these are of articular origin.

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So these are some of the etiologies that have been pro, uh,

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um, suggested

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for cystic adventitial disease trauma

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degeneration from a systemic process, some remnant cells

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during development, but in spinners opinion,

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and I think he's right, um, these actually are coming, uh,

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from the joint and the, we seek examples like this

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where you have cystic adventitial disease

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around the artery, clearly, uh,

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what you would call cystic adventitial disease.

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But the patient also has peric cruciate ganglia.

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Sometimes they have intercondylar notch ganglia.

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Um, and, uh, you know, uh, his idea is, is

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that these dissect along the posterior

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knee, along that, uh, middle gen artery

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that I illustrated for you earlier.

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This is another case.

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Uh, this was a case that was actually post

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Contrast and it filled some of these cysts

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inside the joint.

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And then you can see this track going outside,

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running alongside the popliteal artery.

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So his theory is that you get ganglia

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and instead of coming up along a nerve,

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they come up along a vessel and then can dissect from that

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and extend along the branches of the superior

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and inferior, uh, geniculate uh, artery.

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So I think this is interesting.

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I don't have a big enough collection to be sure,

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but I've noticed this communication long time ago never had

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an explanation for it until, uh, this article from Spinner.

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So this is that middle gen nuclear artery.

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This is the case I already showed you with that artery here.

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And this is taken from, uh, an anatomy article by

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BVI with the dissection showing you this branch.

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It's an unpaired single branch at the

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middle of the knee joint.

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Um, and again, you can get ganglia, uh, tracking along it.

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You can get tumor, uh, tracking along it.

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You can get infection tracking out of the capsule, um,

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along this area.

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So, uh, here's its course.

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Usually comes off a little bit high of joint line

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and then dives down

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to enter into the posterior, uh, capsule.

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Just a little anatomy thing, uh, to be aware of.

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We also used to see these central ganglia,

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and I never knew what caused these, uh,

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but I think they're dehiscing like right along

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that same capsular, uh, issue.

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In this example here, normal on your left, uh, the ganglion

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or cyst from the knee heading out.

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This one did not look like a cystic adventitial disease,

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but it shows that same area of the defect with

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how there's this potential communication

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with the popliteal fossa through that, uh, through

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that area in the, in the capsule, which is dehi,

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where the vessel, uh, enters it.

Report

Faculty

Donald Resnick, MD

Professor Emeritus, Department of Radiology

University of California, San Diego

Mini N. Pathria, MD, FRCP(C)

Division Chief, Musculoskeletal Imaging

University of California San Diego

Eric Y. Chang, MD

Adjunct Professor, Radiology

University of California, San Diego

Brady K. Huang, MD

Clinical Professor of Radiology

UC San Diego Medical Center

Tags

Musculoskeletal (MSK)

MRI

Knee