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Case: Congenital Hydronephrosis Related to Vesicoureteral Reflux

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This nest example is a one day old infant who had, um,

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prenatal UTD two slash three.

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So high risk, um, antenatal congenital hydro necrosis

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who presented on day of life one for follow up, um,

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ultrasound postnatally.

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Um, typically we wait until after 48 hours of life,

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but in cases where there is a sufficient concern, we'll go,

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uh, onto postnatal imaging prior to 48 hours of life.

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So the first thing we'll start with is our urinary bladder.

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Here. We're in the sagittal, uh, longitudinal plane.

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Now we're the transverse plane

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and unfortunately this urinary bladder is not very well

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distended to be able to comment one way

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or the other about normal versus abnormal

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bladder wall thickening.

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But we go to the level of the kidneys

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and here we have our right kidney

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with a nice normal adrenal gland,

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um, superior to the right kidney.

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We have ectasis at a minimum of this kidney.

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Um, we'll keep imaging to see if we see any ectasis here.

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We have measured our AP renal pelvis diameter only at four

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millimeters, and so far I'm not seeing any either central

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or peripheral ectasis.

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One note about the normal appearance of a,

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uh, a newborn kidney.

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They often have this layering academic appearance

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of the renal pyramids.

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Um, in the olden days,

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back in the day when I first started training, we used

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to call this tam horse wall proteinuria.

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Um, but uh,

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there's no tam horse wall protein in the on urine analysis

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of these infants.

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And so we just call this transient, uh, renal p uh,

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renal pyramid hyper genicity.

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It is a normal finding in infants in the first few

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weeks to months of life.

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Okay, so continuing

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to look at the urinary tract dilatation of this right kidney.

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Um, in the, uh, supine position, we only have ectasis,

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no ectasis, either central or peripheral.

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Moving on to the left kidney,

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however, we not only have ectasis,

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but I'm starting to see some central ectasis

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and we'll keep going and we'll see if we see any

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peripheral ectasis either.

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Here we have a nice normal left adrenal gland.

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The adrenal gland should look like an Oreo cookie.

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Um, the, you know, birth is a stressful time

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and so we have relative hypertrophy of, um,

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the neonatal adrenal gland as stress kind

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of goes away over the first weeks, uh, of life,

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these will involute

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and are typically not visualized by about six, uh, weeks

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of age in, in a normal infant.

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So continuing to look at this left kidney, um,

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we have an AP renal pelvis diameter.

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Um, I'm not sure if we're within the parenchyma here,

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but it's at least five millimeters.

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Um, the good news is the AP renal pelvis diameter matters

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less once we start to see this central

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and peripheral ectasis.

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Um, so let's go to our cinematic images to make sure

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that we, um, believe

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that there's not only central, but there's also

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Also peripheral ectasis.

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Yeah, so look at this image here.

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Ectasis, which was smaller than one centimeter,

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which is the cutoff needed to be considered UT DP one.

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But this infant, again, you grade, uh, you assign the, uh,

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the UTD classification based on the presence

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of the most severe finding.

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So there is not only central ectasis,

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but we start to see peripheral ectasis.

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Um, these CAEs here are not toothpick, um,

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sharp, they are blunted.

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And so this is peripheral ectasis. So this is UT DP two.

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So at a minimum, this patient will get a follow-up, um,

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postnatal ultrasound, um, within one to six months of age.

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Um, and at the discretion of the referring physician

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or if this patient presents with, uh, urin, uh,

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a urinary tract infection, this patient will go on to VCUG.

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So this patient about a year of life, uh, later, uh,

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was referred for voiding cyst urethrogram to, uh, help,

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help, uh, identify the etiology

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of the urinary tract dilatation.

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So we start out with the scout image

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to make sure there's no abnormal calcifications,

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no abnormal mass effect, um, you know, nothing funky

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or unexpected, no vertebral body anomalies associated.

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And then we'll go on to place a,

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a catheter in the urinary bladder

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and we will start to fill the urinary bladder.

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It's important to get an early voiding image, um, on VCOG

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because we don't wanna miss a ureteral.

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So a ureteral on the early feeling image will look like a

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loosened round defect at the level of the ureteral.

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If it's an, uh, ortho topically inserting ureter,

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it'll be at the level of the, uh, bladder trigone.

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As we continue to fill, we have more, uh, distension

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of the urinary bladder by contrast.

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Um, as we continue to fill.

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Um, then once we think that the patient is about to void

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or we think that the urinary bladder is adequately

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distended, we will get oblique images to try to, uh,

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visualize number one, the urea vesicular junction.

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But then number two, um,

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if we have a distended urinary bladder in the anterior only

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projection, if you have a little bit

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of reflux contrast in the distal ureter only,

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that will be obscured on the frontal projection

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by the distended urinary bladder.

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Hence, we get these oblique images.

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So we can see a normal insertion

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of this left ureter at the level of the u um, uh,

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uh, bladder trigone.

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But we see contrast reflux all the way to the level

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of the collecting system, which is just at the outside,

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just at the edge of this, um, fluoroscopic spot image here,

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we opened up our field of view to see

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that there is reflux all the way

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to the level of the renal pelvis.

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On that left side, we get an exposure to attempt to try

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to visualize more detail of CES

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to see if there's intrarenal reflux,

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which we don't see on this image.

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We go to the, uh, contralateral oblique to make sure there's

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No, no reflux intravenous

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or, uh, reflux contrast into the distal right ureter

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of this infant, which we don't see this male.

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Uh, we always wanna make sure we have a normal urethra.

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And so, uh, this is a nice comparison to that case

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of posterior urethral valves

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where the posterior urethra is similar caliber

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to the anterior urethra on this voiding last image hold.

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Um, as we are imaging, we are of course looking

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to see if there's any reflux,

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intravenous contrast on the contralateral side.

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We start to see a little bit

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of reflux contrast into the distal ureter on this right

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side of this patient.

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Uh, we go back up

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and look at the kidneys as reflux increases

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when the patient voids.

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And we can see not only, uh, uh, reflux contrast

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to the level of the pelvis, but we see the central

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and peripheral CAEs.

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Um, and so, uh, we will grade this based on, um, uh,

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the level of severity of reflux contrast.

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Since these CAEs are not pointy like a toothpick,

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they're just a little bit blunted.

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This is grade three.

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So grade three re we've grade, uh,

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vesco ureteral reflux grade one.

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It's just in the distal ureter grade two.

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It reaches the level of the renal pelvis,

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but we don't have dilation of the collecting system.

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Grade three not only is a reflux to the level

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of the collecting system,

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but there is some mild dilation of the, um, uh, caly

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grade four, you have, um, more dilation.

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And then grade five is severe ulous dilation

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of the renal collecting systems.

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And this is our final image in this patient.

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We always wanna also make sure that that refluxed contrast

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voids, that there's not a concomitant, uh, uro, uh,

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ureteral pelvic junction obstruction, A UPJ obstruction

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with concomitant reflux.

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But this patient just had sico ral reflux grade three on the

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left, grade one on the right.

Report

Text

Faculty

Judy H. Squires, MD

Associate Professor of Radiology

UPMC Children's Hospital of Pittsburgh

Tags

Ureters

Ultrasound

Pediatrics

Neonatal

Kidneys

Genitourinary (GU)

Fluoroscopy

Congenital

Body

Bladder