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Case: Adrenal Hemorrhage

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This case is a one day old infant

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who had congenital heart disease.

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Um, all of the patients in our population

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who have congenital heart disease undergo screening,

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renal ultrasound, looking for concomitant renal anomalies.

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Um, multiple congenital anomalies often go together.

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So, um, we started

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with renal ultrasound looking at the right kidney.

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So here's a normal looking right kidney.

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Um, we see some normal right adrenal gland

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above this normal looking right kidney.

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Um, this patient, um, uh, does have a little bit

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of a small size of the right kidney,

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four centimeters about is normal renal length

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for a term infant.

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And then we come, um, over to the left side of the kidney

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and we have what looks to be normal

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left reinform shape of the left kidney.

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Um, as we continue imaging, there is, uh, sort

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of an unusual appearance of the left adrenal gland.

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However, so unlike the right adrenal gland that had, um,

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a nice thin appearance

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and we could see that Oreo cookie kind

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of trilaminar appearance of the left adrenal gland.

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Um, this looks a little bit large

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and has some, uh, architectural distortion of that, uh,

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left adrenal gland, uh, left adrenal gland area.

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So, um, the concern anytime you have an abnormality

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of your adrenal gland is, um, in a newborn period,

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is this hemorrhage, so adrenal hematoma

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or is this congenital neuroblastoma,

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which can happen congenitally

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and will involve the adrenal gland.

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So if you can tell if there's blood flow

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to the adrenal gland, that can be helpful

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for distinguishing solid mass, which would lead you toward,

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um, congenital neuroblastoma.

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If you can't delineate blood flow, it could just be

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that the, um, it's like not a particularly vascular, uh,

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neuroblastoma or it could be, um, adrenal hemorrhage.

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So the right thing to do in this patient,

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number one is call the clinician

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and tell them that you have an incidental finding

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of something going on in that left adrenal gland.

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This patient's kidneys are normal, thankfully,

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as is the urinary bladder.

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Um, they can do two things.

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Number one, they will check, uh, urine catecholamines

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to see if they are elevated, which we would expect

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to see in the setting of, uh,

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congenital neuroblastoma is elevated

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urine catecholamine levels.

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Number two, we can just get a follow-up ultrasound

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to see if this abnormal kind

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of enlarged heterogeneous appearance

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of this left adrenal gland resolve spontaneously.

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Um, if it's hematoma

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or uh, adrenal hemorrhage, we will expect that

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to involute over time.

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If it's neuroblastoma, we might see a similar appearance

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or it could enlarge in size as the, if,

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if it's a neuroblastoma that grows.

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So, uh, we'll recommend at a minimum follow up ultrasound in

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this patient with a left adrenal lesion.

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So two weeks later, this patient presented

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For follow-up, uh, ultrasound to make sure that

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that left adrenal, uh, area improved in appearance.

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Um, you can tell they had a difficult time, uh,

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examining this patient because she, uh,

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we are using only our sector transducer.

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We are starting with Doppler assessment

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of the renal vasculature

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because this was a patient with congenital heart disease

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and so there were other concerns to be answered on this.

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Um, ultrasound study.

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We have normal arterial waveforms

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that we've obtained from our main hepatic artery.

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Um, they're actually a little bit high resistance in

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appearance, uh, which could just be related

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to postprandial state.

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Um, our portal vein has normal antegrade flow,

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as does our left portal vein

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and our left, uh,

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hepatic artery have pretty normal waveforms.

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We'll continue through our, uh, uh,

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very bidirectional hepatic venous flow.

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So again, this, this patient has congenital heart disease

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and maybe has an, um, an intrinsic intracardiac shunt

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as the etiology of these very bidirectional, um,

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reversal flow in, uh, um, during the, a prominent a wave

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of this, uh, left of these hepatic veins.

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We have a patent inferior vena cva.

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Uh, what we see of our liver looks like normal genicity

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normal morphology.

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Our gallbladder is completely collapsed in this infant,

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so it's hard to tell what's going on.

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Our right kidney has a continued normal morphology

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with no abnormal urinary tract dilatation.

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The renal vasculature are,

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is patent at the hilum moving along.

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There's a Foley catheter in the completely, um, uh,

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decompressed urinary bladder.

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So we, we can't tell much

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to our clinical colleagues about the urinary bladder

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besides it's decompressed, their Foley catheter is working.

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So we have a normal, uh,

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normal spleen in the left upper abdominal quadrant

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and then we'll try to see if we can find that, uh,

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left adrenal abnormality that we saw on the prior study.

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So we see left upper pole kidney here.

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We have a pretty normal looking left adrenal gland

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above the left kidney.

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Um, thankfully our stenographer has switched

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to the linear high frequency transducer

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so we can see better detail as opposed to

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that prior sector transducer.

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So continued normal looking left kidney.

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Um, we still have some G globular, um, sort

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of heterogeneous, um, hypo material in the region of

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that left adrenal gland,

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but we don't see any internal color doppler flow.

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Certainly there has been no interval enlargement

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of this left adrenal mass like area.

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And so in the absence of elevated urine catecholamines,

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this is almost certainly going to be a left adrenal hematoma

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or left adrenal hemorrhage related to birth trauma,

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especially in this patient with congenital heart disease

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who maybe had a little bit more of a tumultuous, um,

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birth experience than other patients.

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But we'll continue to follow this, um, through

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until the size that it becomes smaller

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or calcified, um, outright in this infant with um, uh,

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just normal, essentially normal birth related left adrenal

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hemorrhage.

Report

Text

Faculty

Judy H. Squires, MD

Associate Professor of Radiology

UPMC Children's Hospital of Pittsburgh

Tags

Ultrasound

Trauma

Pediatrics

Neonatal

Genitourinary (GU)

Body

Adrenals