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Case: Grade 3 Germinal Matrix Hemorrhage

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So this was a one week old,

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former 30 week gestational age premature inference who came

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for screening head ultrasound at one week of life.

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So we start with our baby head transducer in the coronal

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plane going anterior to posterior,

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and right away we see dilated lateral ventricles.

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So rather than that sort of pointy appearance

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of the frontal horn lateral ventricle,

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these are a little bit rounded.

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The next thing we see is, uh,

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there's some subtle academic material on that left side.

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A little bit more obvious on that right side.

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Um, so genic material in the absence of clinical concern

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for infection of ventriculitis type picture

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in a premature infant,

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this is gonna be germal matrix hemorrhage.

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So on both sides, on this left side it's a little bit lower,

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uh, hyper coic material genicity.

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And on the right it's much more genic, um, hyper genicity,

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hyper coic material within that ventricle.

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And we have ventricular enlargement.

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And so right away we know this is gonna be at least a grade

1:00

three germinal matrix hemorrhage.

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As we continue posterior, uh, we see the choroid plexus,

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but there's also this genic material, uh, surrounding

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and sitting on top of the choroid plexus bilaterally.

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Our sonographer put measurements on the, on the ventricles,

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depending what your neonatologists

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and if you have neurosurgeons at your institution, uh,

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depending what they want,

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you might make different measurements.

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There's lots of different ways to measure the ventricles,

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and this is just the frontal horn width

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that the sonographer has measured here at our institution.

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Um, our current protocol,

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we actually measure the ventricular index as well.

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So just touch base with your neonatologist

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or neurosurgeons to decide how, how they want you

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to measure, uh, and report ventricle size.

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But, uh, at any rate, these are mildly enlarged, um,

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lateral ventricle, frontal horns and occipital horns.

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As we go to the sagittal plane, we're coming off

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to the right side here.

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We can see that again, that echogenic material in

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that lateral ventricle that is dilated coming off

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to the left side that remember blood runs downhill

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and most babies aren't getting tummy time in the nicu.

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Most premature infants are at a minimum on some sort

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of positive pressure ventilation

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or they're intubated in the ICU

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and so they are gonna be in the supine position.

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So blood is gonna roll dependently in the lateral ventricle.

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So always make sure you're looking along the, um, atria

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and posterior most aspect of the lateral ventricles

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to look for hemorrhage.

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Um, but we could see it on the frontal view

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and the frontal horn, lateral ventricles

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as well in this infant.

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Um, this is a premature infant

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because as we are looking at our cinematic images

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as we go from anterior to posterior,

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we do have some cingulate sulcus formation.

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Um, also our clinicians have told us this

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patient's gestational age.

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So, um, uh, we know that this is a premature infant.

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So unfortunately bilateral grade three germinal matrix

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hemorrhage, we do see also a little bit

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Of, of hemorrhage that has extended into this, uh,

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third ventricle here in this infant

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with bilateral grade three germinal matrix hemorrhage.

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So after this infant screening had ultrasound, um,

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the patient came to MRI

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to further delineate the abnormalities.

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So we'll start on this sagittal T one weighted, uh, MRI

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where you can see there's this abnormal T one hyperintense

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blood layering dependently in the

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dilated lateral ventricles.

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Uh, this one is not so much dependent,

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but we don't see any other abnormal T one hyperintense foci

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in the brain parenchyma of this infant.

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The ventricular mele, you're gonna be able

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to see a little bit better on these axial images.

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So we have dilated lateral ventricles.

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Third ventricle is at the upper limit of normal.

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Fourth ventricle is normal in caliber,

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but we can see this T two, uh,

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low signal hemorrhage layering dependently in these, uh,

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dilated lateral ventricles.

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Um, similar findings are seen on this T one weighted axial

3:57

sequence where the hemorrhage is hyperintense in signal.

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And then I think the susceptibility weighted images are

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where you can see hemorrhage much, much better.

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You get that susceptibility related to the hemosiderin.

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So lots of low signal susceptibility related to this,

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this hemorrhage bilaterally in this

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infant's dilated ventricles.

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So bilateral grade three germinal matrix hemorrhages

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confirmed at MRI.

Report

Text

Faculty

Judy H. Squires, MD

Associate Professor of Radiology

UPMC Children's Hospital of Pittsburgh

Tags

Vascular

Ultrasound

Pediatrics

Neuroradiology

Neonatal

MRI

Brain