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Case: LungRADS S-Modifier - Moderate Coronary Arterial Calcification

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0:01

Let's approach this case from the perspective

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of incidental findings on the soft tissue windows.

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While the soft tissues on a low dose screening CT are going

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to be noisy, particularly above the shoulders

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where there's a lot of bone tissue in the humeral heads,

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the scapula and the clavicles,

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you can still see the anatomy quite well.

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You certainly don't have the detail of a standard dose exam,

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but remember, this is a screening exam.

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It's a public health tool to identify early evidence

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of lung cancer for the purpose

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of reducing lung cancer mortality.

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It is not considered a full diagnostic chest CT examination.

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One of the things that we readily see on the soft tissue

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windows is looking for abnormal calcification

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as individuals age the calcium, for example,

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deposits in the rings of the trachea.

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So we see calcium there.

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As we're looking to the airway, we see this little kind

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of smooth low density lump along the edge here.

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This patient has a lot

0:59

of secretion sitting in their airway right here,

1:01

a big area of mucus.

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This is common in patients who smoke cigarettes

1:06

who have chronic bronchitis

1:08

and evidence of small airway disease.

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So whenever I see mucus plugging in the trachea

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or in the small airways is common in individuals

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who smoke cigarettes.

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It often has this frothy appearance with air bubbles in it.

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It's common in individuals who smoke cigarettes

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because of the association with chronic bronchitis

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and small airway disease.

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So whenever I see it on cts, I'm going to report this type

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of airway abnormality.

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If airway findings are solid without this sort

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of frothy air bubble appearance, if they're not linear

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and if they are adherent to the non-dependent wall,

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then we get concerned about them being endobronchial

1:45

malignancies such as carcinoid tumor.

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These are relatively uncommon in lung cancer screening

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compared to other incidental findings.

1:54

Going back to our soft tissue windows,

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we can see a little bit of calcium in the thoracic UTA

1:59

on our chest CT reports.

2:01

Here at our institution, we not only report coronary calcium

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as a non mild, moderate, severe score currently,

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and we're investigating using an AGA

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and score on all of our chest CT exams.

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We also give a visual grading for

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thoracic retic calcification.

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Not sure what the scientific evidence is yet to prove

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that its benefit, but you have to start somewhere in trying

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to change practice and understanding what we see

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and what its implications are.

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Of course, the most common cardiovascular calcification

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we're gonna find is coronary calcification.

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As we're scrolling down here,

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we can see calcification in the expected location

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of the left main and proximal left anterior

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descending coronary arteries.

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Calcification and coronary disease,

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particularly at those locations, makes a patient higher risk

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of cardiovascular events than smaller calcification in the

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more peripheral portion of the cardiovascular tree.

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So not only is it important

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to report coronary calcium using a non mild moderate visual

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score, or potentially

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to give it a quantitative score if you're using those sorts

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of software tools, but particularly

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to point out if it's in the left main

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or proximal LAD in the radiology reports.

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So here we have multifocal calcification

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in the left circulation, the expected direction

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of the LAD here coming down LAD,

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we see some extending posteriorly here,

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which is in the left circumflex coronary territory.

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And we see some anteriorly here in the right AV groove

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where the right coronary artery is.

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So we have triple vessel coronary calcification.

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It's somewhat scattered,

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so this amount would fall into the moderate visual coronary

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calcium scoring strata,

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which would make this patient at intermediate

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to moderate risk of future coronary events.

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Moderate coronary calcification is important

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to report on your lung cancer screening cts moderate

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or severe because cardiovascular risk assessment

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and risk management is particularly

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important in these patients.

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We have the opportunity

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to see this patient's lung cancer screening cts

4:09

over several years.

4:10

We have 20, 24, 20 22, 20, 21, and 2019.

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So this is not a new finding.

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Tson scores can be used

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to quantify changes in coronary calcium over time.

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Visual scoring is a little bit less accurate at measuring

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change going from say, mild to moderate to severe.

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But atkisson scores are being applied serially in some

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patients with high cardiovascular risk in clinical practice,

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usually those being managed by cardiovascular specialists

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or primary care physicians with particular expertise

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of interest in cardiovascular disease risk mitigation.

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So we can see this patient has had this coronary calcium

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present for several years now that we have been, uh,

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doing lung cancer screening.

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cts. You'll notice this one exam in the middle doesn't look

4:57

quite as noisy because along the way,

5:00

the patient had a high resolution CT

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to look at their lung disease findings.

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And we'll take a look a little bit at emphysema

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as we talk about this later.

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But looking at emphysema, quantifying emphysema

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and looking at progression

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of emphysema is importantly recognized as something

5:19

that we should be doing in our patients

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who have lung cancer screening

5:23

and it has significant impact on their patient, uh,

5:26

mortality and potentially morbidity.

Report

Faculty

Ella A. Kazerooni, MD, MS

Professor of Radiology, Cardiothoracic Division

University of Michigan

Tags

Oncologic Imaging

Mediastinum

Lungs

Coronary arteries

Chest

CT

Acquired/Developmental