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Introduction to Airway Nodules

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Airway nodules on lung cancer screening CT are not very

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common, but when they occur, it's important for us

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to recognize when they become actionable

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and when they simply represent evidence

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of underlying lung disease such as asthma

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or chronic bronchitis, different forms

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of chronic obstructive pulmonary disease.

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We're gonna talk about the lung rads categories

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for airway nodules, which was first introduced

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with Lung RADS 2022,

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and the follow-up recommendations that come

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with that categorization.

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Another important feature to consider

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among airway nodules are things we're used

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to seeing every day on cha cts,

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which are secretions in the airway.

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When can you cause something secretions

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or moid impaction evidence of small area disease

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or when does it become an actionable nodule?

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So we'll look at some cases, about half a percent

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of lung cancer screening CT exams will have

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an endo bronchial lesion.

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And by this I don't mean things

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that we consider secretions when we look at them.

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Over 96% of these do resolve on followup imaging,

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and most of them that don't are benign.

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But within this group, there are cancers

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in the Dutch Belgian Nelson trial for lung cancer screening.

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22% of cancers missed on the initial screening

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or endobronchial.

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And by this I mean primarily segmental lobar

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and rarely distal trachea.

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The category for lung rats of

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where endobronchial nodules go in the schema are based on

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location morphology, the number of them,

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and if they persist on followup cts.

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Category zero, meaning we don't score it in lung rads,

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are the typical findings of endobronchial secretions.

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They're often linear.

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If they're lumpy, they have little bits

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of air mix within them, they look sort of frothy

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or they may be branching in tubular.

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We start to get into the lung rads numbering of two four A

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and four B with category two, an endobronchial nodule

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that is a subsegmental airway nodule

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or air within an airway nodule in the absence

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of a soft tissue component

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or mean attenuation less than 21 household units.

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This was the best way for us to describe things

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that are probably secretions.

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Therefore lung rads two negative screens,

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but we will want to follow them on the next annual screening

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CT category four A.

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This is where we get concerned

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and want to do interval follow-up is when we have a

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segmental or proximal airway nodule without the benign

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features of low density or air within them.

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And for these, we recommend a three month low dose ct.

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Typical of the four. A recommendation category

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when we get most concerned are the nodules

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that are in the four B category.

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These are endobronchial nodules that are in segmental

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or larger airways that are persisting on follow-up cts,

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or grow over time.

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These should be referred

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for clinical evaluation and bronchoscopy.

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One of the questions I commonly get about endobronchial

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Nodules, is there anything we can do to prevent some

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of these nodules from even showing up on our lung cancer

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screening cts?

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What I usually recommend is that our imaging technologists

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who are acquiring the CT images, when the patient comes

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for their exam, ask the patient to take several deep,

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big coughs before they lay down on a scatter table.

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This can help them clear small areas of secretions

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that we won't have to see on the CT examinations

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because of this simple intervention.

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So a few good coughs

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before laying down on the CT table can prevent you even

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having some of these on your images to look at.

Report

Faculty

Ella A. Kazerooni, MD, MS

Professor of Radiology, Cardiothoracic Division

University of Michigan

Tags

Oncologic Imaging

Neoplastic

Lungs

Chest