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Case: LungRADS 4B - Cystic and Solid Nodule

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Let's take a look at this screening CT

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and a 62-year-old man with a 40 pack year history of smoking

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who currently engages in cigarette smoking.

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Very important as a radiologist in practice to

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involve patients in smoking cessation activities when they

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come for lung cancer screening

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as an important touch touchpoint in the radiology department

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for potential tobacco consultation cessation.

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So as we're scrolling through this exam, we can see a bunch

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of little tiny low density holes with no walls.

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So some mild central lobular emphysema

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and an occasional little micro nodule.

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One right here anteriorly in the right upper lobe.

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Another one up here, anteriorly left upper lobe.

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So a number of these sub centimeter, four millimeter,

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two millimeter nodules,

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which will all be lung rads category two screens.

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We're seeing some small airway wall thickening

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with small airway lumens.

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This person has airway predominant COPD

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with extensive wall thickening,

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but now we're coming into a lesion in the right upper lobe.

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It has solid components. Let's blow this up a little bit.

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It has solid components,

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but it also has cystic components,

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several cystic components.

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So this is a mixed nodule with cystic and solid components.

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The overall size of this lesion was 28

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by 24 millimeters when it was measured.

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I think some of the AI tools can have difficulty measuring

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lesions that are this complex.

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They might only measure the solid component

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and think of the cystic component

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because it's eccentric as maybe just emphysema

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and not included in the overall cyst size.

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So some of these more complex ones, it's important

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to maybe do your own hand measurements,

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look at it in three dimensions

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because they can be irregular in shape

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and every lung cancer is not a perfect round sphere.

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It can be ovoid. They can certainly have different sizes

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in different diameter.

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So if we look at this here in the coronal images,

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you can see it's wider than it is tall.

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So sometimes you wanna measure it in the coronal sagal axial

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plane to find the largest um area.

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In a nodule like this,

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you also wanna measure the largest solid component in

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addition to measuring the overall size of the lesion.

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So because of the complex nature with a combination of cys

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and solid nodules, this would be a long rats four B lesion.

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And you would get there whether you either came at it from a

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solid nodule recommendation

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or whether you came at it

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through the cystic nodule recommendation schema, both

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of them would get you to category four B.

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We don't wanna forget to look at the rest of the lung

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and just be focused on that.

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Looking for other pulmonary nodules, again, we see more of

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that extensive smaller wall thickening

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and flip on our mips, again, helps us find

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Nodules.

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And you can see they just kind of pop out in the background

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relative to the pulmonary vessels,

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almost like little buds on a tree at springtime, after all.

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So a cystic lesion

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with excentric nodularity category four B.

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This patient subsequently underwent a right upper lobectomy,

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and this was an invasive adenocarcinoma

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with some mucinous features we wouldn't be able

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to detect whether it was mucinous.

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We usually look for areas of ground glass

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for mucinous adenocarcinomas, but we don't see that.

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So an invasive adenocarcinoma, right upper lobectomy

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and a complex part cystic part,

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solid multi lobulated nodule on lung cancer screening, CT

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and an asymptomatic individual.

Report

Faculty

Ella A. Kazerooni, MD, MS

Professor of Radiology, Cardiothoracic Division

University of Michigan

Tags

Oncologic Imaging

Neoplastic

Lungs

Chest

CT