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Case: Typical Medulloblastoma

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So this is sort of a typical case

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of myoblasts in the fourth ventricle.

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Enhances. Now there's some metastatic deposits we see here,

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intracranial, a metastatic deposit

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and a spinal metastatic deposit.

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It fills the fourth ventricle

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and notice it's relatively hyperintense on T two, um,

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that were, that's become gonna be relevant.

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It was also hyperdense on ct that's relevant

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because if you think th these have a high nuclear

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cytoplasmic ratio, so relatively low cytoplasm,

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cytoplasm is fluid, which is bright on T two.

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So less fluid, more cellular, darker on T two,

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less fluid, more cellular, brighter on ct.

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So this is now showing

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that these MR imaging characteristics,

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it's not just different images

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and something's bright, darker, you know,

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but they actually give you an insight into the, um,

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the, you know, microcellular structure

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of these, of these tumors.

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And that can help guide us in figuring out what's going on.

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There's low diffusivity, um, quantitative was six 50, um,

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which is low.

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If we look, re remember that chart from

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before, only medulloblastomas were, um, were at

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that level on that chart.

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So low diffusivity implies a high nucleus cytoplasmic ratio,

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and as I mentioned, the high nucleus cytoplasmic ratio

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corresponds to relative increased density on CT

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and intermediate to hypo intensity appearance

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on T two weight imaging.

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So these are all different things that are related

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and can be explained by the actual, um, uh,

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histopathology of MedU neuroblastoma.

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And the imaging features

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of this overall suggests group three.

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It's a fourth ventricular tumor that's enhancing.

Report

Faculty

Asim F Choudhri, MD

Chief, Pediatric Neuroradiology

Le Bonheur Children's Hospital

Tags

Oncologic Imaging

Neuroradiology

Neoplastic

MRI

Brain