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Case: SHH-activated Medulloblastoma

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Here's a patient with a mass in the periphery

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of the left cerebellar hemisphere

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with some internal microcystic areas.

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There's edema seen antra medially

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to it in the left cerebellar hemisphere.

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If you look on CT again, the, the mass,

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the solid portions of the mass, uh,

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have relative increased density on ct.

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The microcystic areas ha are, have, are hypo intense

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and the, there's also a hypodense appearance

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of the parenchyma that where there was, um, edema,

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there's heterogeneous post contrast enhancement of this mass

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and reduced diffusivity of the solid portions of the mass.

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So the facilitated diffusion is seen in the,

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um, cystic components as well as in the cerebellar edema.

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So overall, this is a sonic hedgehog activated

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medulloblastoma, which in the hi, the,

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um, histologic classification is typically going to be a,

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uh, desmoplastic nodule.

Report

Faculty

Asim F Choudhri, MD

Chief, Pediatric Neuroradiology

Le Bonheur Children's Hospital

Tags

Oncologic Imaging

Neuroradiology

Neoplastic

MRI

Brain