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Mucociliary Clearance

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The understanding of the flow of mucus

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through the perinasal sinuses was based in

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work that was done largely at Johns Hopkins

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Hospital by two of my good friends, David

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Kennedy and Jim Zinreich, along with, uh,

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scientists from Europe named Heinz Stammberger.

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And what they found was that there is a

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natural flow of the mucus that goes through the

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various ostia that I've previously described.

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This is probably better understood using

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this sagittal reconstruction of a diagram

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that you see on the right-hand side.

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In this diagram, you see that the mucus of the

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frontal sinus goes through that ostium that I

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had previously mentioned, the frontal recess.

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And from there, it goes into the common pathway,

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which is that middle meatus that you will see

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drains a number of the different

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areas, including the maxillary sinus.

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You notice also that the ethmoid sinuses

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are also draining down and through and into

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the middle meatus in the anterior portion.

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The posterior ethmoid air cells, however,

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have a separate drainage, and that is through

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what's called the sphenoethmoidal recess.

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However, even the sphenoethmoidal

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recess, as you can see, drains downward and

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posteriorly to the pharynx and into the back

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of the posterior portion of the middle meatus.

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This was very important work because

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it substantiated the value in doing

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functional endoscopic sinus surgery.

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So this is abbreviated quite often as FESS.

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You'll see "status post FESS" on your request slip.

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Functional endoscopic sinus surgery

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was a reaction to the failure of

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the previously done surgery, which was called

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the Caldwell-Luc procedure. The Caldwell

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Luc procedure was one that was done under the

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upper lip, creating a hole in the floor of the

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maxillary sinus, which you see over here.

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And then creating another opening in the inferior

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aspect of the medial wall of the maxillary sinus.

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The idea being that by opening up this

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hole, the sinus material would then drain

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inferiorly and then back into the pharynx.

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In point of fact, that's not the way the

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mucociliary clearance — the cilia beat

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the mucus up and out and into the ostium.

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So this surgery that was done for many, many years, 51 00:02:35,125 --> 00:02:37,674 was not very successful, and patients

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kept coming back with chronic sinusitis

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despite the Caldwell-Luc procedure, which

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was the inferior maxillectomy and antrostomy,

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functional endoscopic sinus surgery,

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by contrast, generally opened up the narrow airways

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in order to facilitate the

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normal mucociliary clearance.

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So what is typically done in this situation

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is that the uncinate process is removed,

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so that way there's a larger passageway

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from the maxillary sinus into the middle

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meatus, and that also facilitates the anterior

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ethmoid sinus drainage as well as the

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frontal sinus drainage, because the uncinate

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process is frankly in the way, if you will.

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Similarly, for sphenoid and posterior ethmoid

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sinusitis, instead of opening up those sinuses

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and taking down their walls, what people now

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do is they do a sphenoidotomy, which is an opening

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to that drainage pathway, so you're continuing

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to use the normal mucociliary clearance of

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the beating of those cilia, moving the mucus

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the right way, but just through wider channels.

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That is why it's functional

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endoscopic sinus surgery.

Report

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Mahla Radmard, MD

Postdoctoral Research Fellow

Johns Hopkins University School of Medicine

Tags

Sinus

Sinonasal Cavity

Oncologic Imaging

Neuroradiology

CT

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