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Esthesioneuroblastoma

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Olfactory neuroblastomas on MR are centered at

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the skull base, at the olfactory cleft region of

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the nasal cavity, and then may grow intracranially.

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They don't have to grow intracranially. When they do,

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we wanna look for that cystic component,

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as you see here on this T1-weighted scan, the fluid

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signal intensity posterior along this tumor.

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Here is the mass in the nasal cavity extending

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intracranially through the ethmoid sinus, and

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then along the posterior margin, the cystic

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portion of the tumor, which corresponds

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to the low signal on T1-weighted scans.

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And on the post-gadolinium enhanced

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scan, you see the cystic component,

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which is posterior without solid enhancement.

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So looking at this tumor, particularly if we

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saw it on the coronal image and noted the

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involvement right at the skull base

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along the cribriform plate and the cyst,

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we would suggest a specific diagnosis

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in this case of olfactory neuroblastoma.

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So we finally have one that we can sort of make

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a good guess as to the histology on this tumor.

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Fortunately,

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as with many of these, you can see that there's

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a component of this that's in the lower nasal

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cavity where they're gonna be able to get a piece

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of tissue quite easily and make the diagnosis

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histopathologically before the attempted resection.

Report

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Mahla Radmard, MD

Postdoctoral Research Fellow

Johns Hopkins University School of Medicine

Tags

Sinus

Sinonasal Cavity

Oncologic Imaging

Neuroradiology

Neoplastic

MRI

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