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Esthesio / Olfactory Neuroblastoma

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So we may be getting a little frustrated

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because we can't make histologic diagnoses

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on most of these sinonasal cancers.

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One of the lesions that has a typical location and a

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somewhat typical imaging features is the

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esthesioneuroblastoma or the olfactory neuroblastoma.

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This is a lesion that occurs in the high nasal

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cavity, along the olfactory cleft, and therefore

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has a predilection for growing intracranially.

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This is a CT scan showing an esthesioneuroblastoma.

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This is another CT scan showing one of the features

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that might suggest this diagnosis, speckled

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calcification in the skull base portion of this

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esthesioneuroblastoma. From the upper

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nasal cavity, it may grow intracranially,

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and when it grows intracranial, you may

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see cystic areas associated with it.

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For example, in this case, we see

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the involvement of the nasal cavity.

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We see the growth intracranially, but we

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also see associated cysts that are at the

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periphery of the top of the cancer as it

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interfaces with the intracranial contents.

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This peripheral cystic area in a tumor that is

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26 00:01:15,105 --> 00:01:19,635 centered on the olfactory cleft region and upper

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nasal cavity, showing contrast enhancements,

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still being dark on a T2-weighted scan,

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would be characteristic of an olfactory neuroblastoma.

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This is a different case of

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an olfactory neuroblastoma.

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Again, growth through the cribriform plate, along

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the crista galli from the upper nasal cavity.

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In this case, no cyst associated, dark

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in signal intensity in T2-weighted scan.

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Again, features that would be characteristic

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of an olfactory neuroblastoma.

Report

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Mahla Radmard, MD

Postdoctoral Research Fellow

Johns Hopkins University School of Medicine

Tags

Sinus

Sinonasal Cavity

Oncologic Imaging

Neuroradiology

Neoplastic

MRI

CT

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