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Delayed Imaging

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So why might you want to do delayed imaging as part

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of a, a coronary ct?

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Uh, well it's been shown in some studies.

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Uh, here's one that our group looked at, uh, that the

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addition of multiple phases can help your specificity.

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So this is a CT p CT perfusion exam,

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and you can see this is a heavily diseased patient, somebody

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with known, uh, coronary artery disease.

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And you can see the calcium makes the coronary

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CT very hard to read.

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So this is the LAD,

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but I'm also showing you here's a profusion

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defect in the first pass.

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And so you have hypo enhancement

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and that correlates in the circumflex

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to the circumflex occlusion that you can very clearly see

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by the invasive angiogram

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and is hard to sort out in the, uh, CT angiogram.

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There's lots of calcium, it's also visible.

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Um, but you see here a circumflex perfusion defect

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and you see that the RCA while disease

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and very hard to look through on A CTA is patent

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by angiography.

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Conversely, if you add a delayed image,

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you can sort out what's not just hypoperfusion

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during stress, but or at first pass,

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but actually an infarct.

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So here's another case. This is a patient

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with a longstanding LAD occlusion

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and I'm showing you matched MRI and CT images.

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And you can see a transmural infarction

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by late gadolinium enhancement.

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You can also see that same thing by ct.

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So whether you use a CT

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or an MRI, you are looking at small molecules getting

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into that fibrous scar.

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So there's a complete transmural infarct of the apex here.

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Um, and so you can look at a

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CT protocol to be comprehensive.

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You can use different modes,

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but basically by getting a non-contrast, a contrast

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and delayed images that might help you, uh, sort out the,

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uh, presence of an infarct.

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And you can do that with either modality.

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So in, in summary, you can actually, from a coronary ct,

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you get the anatomy looking at the coronary arteries,

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you can look at relative profusion defects.

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Here's a patient with a diagonal occlusion.

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It was acute, so this is first pass.

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You can look at the myocardial function, uh,

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which we are gonna often get while just acquiring

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your coronary ct.

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Um, and you can also get a late image

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and look at, uh, infarct.

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Now the first line is usually gonna be an MRI

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to look at late enhancement,

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but a CT can certainly do it if it's needed.

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And sometimes you get it whether you are,

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uh, looking for it or not.

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If you especially, uh, doing a coronary CT combined with,

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say, in a chest CT

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or an abdominal ct, you might be acquiring late phases.

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So those are the kind of, uh, basic parameters

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with which you can sort out ischemic coronary disease.

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Uh.

Report

Faculty

Brian Ghoshhajra, MD, MBA, MSCCT

Academic Chief, Cardiovascular Imaging and Associate Chair, Operations Analytics

Massachusetts General Hospital / Harvard Medical School

Tags

Vascular

Coronary arteries

Cardiac

CTA

CT

Angiography