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Severe Stenosis With Serial Lesions, Emergency Chest Pain

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0:01

Next case is a common use of CT in some settings.

0:05

Uh, and this is an emergency chest pain patient.

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And what you have is, um, somebody that had a

0:13

stressful situation created substernal chest pain

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and they had the high sensitivity troponin

0:20

that most hospitals are using now.

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And it was elevated but low. So it was the values we use.

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Um, it came out 26

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and 22, so it was positive trended downward,

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but really you're not clearly an MI until you're

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around a hundred and beyond.

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So this is, uh, something you have to explain.

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And there is a differential myocarditis,

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the pulmonary embolism all, in fact,

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this person had a PE rule out

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and they didn't find one, so they proceeded further.

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So, um, well coronary artery atherosclerosis

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confirmed by the calcium score very high.

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In fact, let's just say what this is. 1,876.

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Um, we never stopped there. Uh, I'm gonna look at that rca.

1:00

And already I'm pretty, uh, concerned, uh, about potential

1:05

for somewhat proximal disease.

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Let's turn this on its axis

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and nothing severe.

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My guess is this is at worst, moderate,

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and maybe even just mild

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'cause it's very densely calcified this distal RCA though

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little harder for me to say.

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Anything smart about that. Let's just double click on that

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and look at another view.

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Yeah, and these smaller the vessel, the more

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inaccurate you're gonna be

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because you, you're, it's harder to see the findings

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and there's more motion and noise.

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So at least moderate distal RCA and probably mild proximal.

1:39

Now we're gonna move on and look at the left main

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and commandment.

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Number one, thou shalt not miss left main disease.

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There is a, um, very short left main here

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and you can see it immediately bifurcates,

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and I don't think I would call it severe.

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Sometimes when I'm worried about a left main though, uh,

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I like to do an area measurement that tends

2:01

to correlate pretty well with intravascular ultrasound, uh,

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which is a way an interventionalist can use

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to decide if something's significant

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in this case, why not?

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Let's do a, uh, so you just make a little ROI.

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So this area is 7.1.

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I might be a little bit liberal on my, uh, drawing there,

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but the, I'd probably be even higher.

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4.5 millimeters

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and lower millimeter squared is, uh, tends to correlate

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with the positive cases.

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Some studies have shown seven,

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but this is gonna be beyond seven,

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so I think it's probably not left main disease.

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There's irregularity. It'll, it'll be disease

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but not severe disease and significant disease.

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But when I look at this LED, I see tons of calcium.

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I know there's some blooming artifact

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that's gonna hamper my accuracy, but it's way too long.

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And I see kind of small lumen there.

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I always like to look at a couple views through it.

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This is a couple of series

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of at least moderates, maybe even severes.

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Um, and then you can see the native distal vessel.

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And even beyond all those branches,

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it's still a almost three milliliter vessel.

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So this is a positive till proven.

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Otherwise I just happen

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to land on the circumflex on this view,

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but I already don't like what I'm seeing.

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Just gonna MIP that for you to, to move through,

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but, okay, so irregularity

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and maybe a moderate due to densely calcified,

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partially calcified plaque.

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Um, let's just do a little bit

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of a MIP in the lateral view here just to, um,

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look at those oms.

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Oh, okay. So, but again, there's a,

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this is an OM turning into an, uh, from,

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from the circumflex, but that's positive.

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So series of probably moderate lesions in the OMS serial

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stenosis, at least moderate, maybe severe in the LAD, uh,

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and then a distal RCA.

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So what happens next?

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One could argue no, even if you did an FFR

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or something fancy like that,

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it's not gonna change management.

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The next step should be what came next,

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which is an invasive angiogram.

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So I hope if you work at a, a hospital that does lots of,

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um, ct,

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but even a small amount, you should follow up your cases

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and see what the catheter angiogram shows.

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And we do it systematically.

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So we've done it intermittently through the years.

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And now we've got a program where anyone

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that gets a CT gets tagged and watched.

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And if they have a follow-up cath, then we like to correlate

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and make sure that we are accurate.

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And new readers are always honing their eyes.

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So, um, this is

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what you're getting in this course right now, of course.

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But, um, I see some irregular, some disease there.

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It's not as impressive, uh, on this view by, uh, calf,

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but we know that, that the, they get less affected

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by blooming artifacts.

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So probably serial mild stenosis, a lot of tortuosity.

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I think I was worried about an OM there.

4:41

Wow, that doesn't look nearly as bad as I thought I'd see.

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I think though there is a fair amount of disease there.

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Looks to me like that was, um,

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bothering the interventionalists too.

4:56

They shot the RCA, okay, not the worst.

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Some, some mild disease.

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And they actually agreed with other,

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there's enough irregularity probably worth pursuing.

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And what you'll see here is they went on, um,

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put some wires down, uh, and did some complex work.

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And what ultimately happened was the LED, which also looked

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to me like our, our worst stenosis was, uh, LED.

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And the second diagonal were both stented.

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You can see that in progress there.

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Let's look at our angiographic result.

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The, uh, IFR, which stands for again,

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instantaneous freeway ratio that, uh, is um, similar

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to an FFR, uh, and that it's measuring flow

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and, uh, better predictor than just anatomic stenosis.

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So positive confirmatory

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and um, probably in the setting of

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what would be considered an acute coronary syndrome

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because whether

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or not the troponins were leaking, it was a,

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uh, acute chest pain.

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We did have a mild troponin leak and, um, disease

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That correlated. So

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it would be unstable angina

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and in this case actually an N stemi.

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So a non SD elevation, MI because there was troponin leak.

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So a very appropriate use for both CT

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and for invasive angiography.

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In fact, the most appropriate for both.

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Um, we know that severe stenosis is an elective phenomenon

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if there's not an acute, uh, chest pain to go with it

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and a somewhat complex stent

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'cause it was a bifurcation stent of this, uh,

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dag in this LED, so complex disease.

Report

Faculty

Brian Ghoshhajra, MD, MBA, MSCCT

Academic Chief, Cardiovascular Imaging and Associate Chair, Operations Analytics

Massachusetts General Hospital / Harvard Medical School

Tags

Vascular

Coronary arteries

Cardiac CT (SCCT Cat B1 Video Case)

Cardiac

CTA

CT

Angiography