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Wall Motion and Function

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So one of the things we've touched on is wall motion

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and a CT can look at, um, left ventricular volumes

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and functions if acquired correctly.

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So you're probably familiar with MRI

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and Simpson's role where we take the ventricle

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and we slice it up into different planes, look at the area

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of each of the planes in the, the tubular ventricle,

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and then, uh, account for the slice thickness and any gaps.

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And then just do simple math.

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So a sum of of areas turns to volumes,

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and you can look at end diastolic volume.

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You can do the same thing at systole

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and then just do simple math to get an ejection fraction.

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So here's how we do it with an MRI, you would, uh, draw each

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of the circles and have the computer figure

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out the areas for you.

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And then take end diastolic volume,

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minus the systolic volume over the end diastolic volume

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and give an ejection fraction, which is the percent of blood

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that's ejected by the ventricle in each beat, knowing

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that normal is at least 55 and almost always less than 72.

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However, um, a CT can skip a lot of those steps

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and just measure volumes the way we would measure tumor

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volumes or, uh, just taking a 3D volume.

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Same concept though, same math.

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It would get somehow the end diastolic volume

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and the end systolic volume, uh, divided

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by end diastolic volume.

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Uh, another very important concept when you're looking at

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the uh, uh, ejection fraction is you need

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to acquire end systole and end diastole.

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So certainly you don't wanna truncate your acquisition.

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So if you're doing prospective trigger

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techniques, you can't do function.

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You wouldn't have your true end systole. End diastole.

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Now, if you're lucky enough

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to acquire the whole cardiac cycle,

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and you may want to protocol things that way, um,

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there's some other things you should think about when one

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of them is getting motion free images.

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So when you're looking at coronary motion, we know that the,

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uh, sweet spot, if you have it in a slow

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and steady heart rate, would be mid to late diastole.

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So that's the imaging point

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where there's least motion in all coronary segments.

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By the way, the orange vessels here are one segments, one

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through four, that's the right coronary artery segments.

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Um, five and further are the LAD and circumflex.

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So if you were lucky enough to have a slow

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and steady heart rate, you would try

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to choose a period in mid to late diastole

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because there'd be less motion this's a second quiescent

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period at mid to late systole,

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and that extends into early diastole.

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And so when you look at in systole, um,

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there's a relatively slightly larger amount of motion,

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but you may have only that choice,

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especially if you have a high heart rate,

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because the faster heart rates tends to, um, mean

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that systole is a fixed phenomenon.

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Diastole is relatively flexible and diastole shrinks.

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Uh, at some point there's almost no

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diastole and no time for filling.

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Um, most of the heart rates

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that we image in in cardiac imaging are gonna be in a

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reasonable rate, but it's often preferable

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to have some systolic imaging in case you need it.

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And if you have the entire heart cardiac cycle,

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then you can look at your ejection fractions,

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look at wall thicknesses.

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Here's an example just to show you, um, that,

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that right coronary artery is the one that moves the most,

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and it's just the way that anatomy is shaped.

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So the center of the chest is in the, um, all over

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The spine here. And what

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you see here is

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that the left anterior descending on this axial image, uh,

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is moving the least.

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The circumflex is in the left AV groove

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and it moves the second most,

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and then the right coronary artery moves the most.

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And that's what this graph shows you as well,

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that the right coronary outta velocity is get the highest.

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So if you're gonna have a coronary motion artifact issue,

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it's probably gonna be in your right.

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And if you don't have it in diastole, you may have

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to look in systole.

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And I'll show you many examples of both diastole

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and systole throughout the course.

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By the way, it's good to talk

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and think about radiation dose.

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So if you throw away all data

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and only acquire it one point, if you think you can nail it,

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prospective triggering allows you to reduce radiation dose,

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but it closes the door

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to looking at the wall motion and the function.

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Uh, and again, you need to look at every segment

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of the coronary arteries

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and see them well to preserve

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that high negative predictive value.

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So it's very important to get motion free images

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of every coronary segment.

Report

Faculty

Brian Ghoshhajra, MD, MBA, MSCCT

Academic Chief, Cardiovascular Imaging and Associate Chair, Operations Analytics

Massachusetts General Hospital / Harvard Medical School

Tags

Vascular

Coronary arteries

Cardiac

CTA

CT

Angiography