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Role of CT FFR in Translesional Gradient Evaluation, Low-risk Patient in Mid-40s

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So our next case is a 44-year-old, so lower on the end

0:05

of the age spectrum with some risk factors.

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One thing led to another

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and got this CT just showing you that

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he has more calcium than some

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of the elderly patients we've looked at.

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So, um, the, uh, disease doesn't respect textbooks

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or boundaries, but bottom line, the test was selected

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and patient came for this CT angiogram.

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And I'll just jump right to some C views here just

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to show you more than his share of disease, especially

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for age, but with these kinda moderate a series

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of maybe moderate, uh, or moderate and mild lesions.

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And then a distal, uh, RCA stenosis back

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to the left, some disease,

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but not obstructive disease in the left main.

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But I wanna lay that out carefully

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because distal left main can be a pitfall.

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And uh, I do see what looks like very osteo, LAD,

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not the worst, maybe mild, but it's a lot of plaque.

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Uh, and then some really dense calcification here.

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So I'm just gonna reorient.

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So yeah, I'm pretty worried there's a, maybe some

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relatively small vessel sizes there that don't help us any.

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It's very difficult to assess stenosis when you

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don't have a lot of anatomy.

1:25

Um, the circumflex,

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I'm watching it, that's a much bigger vessel.

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Uh, looks pretty good. So I would say that there is osteo

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mild and mid moderate LAD densely calcified plaque,

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and then a series of moderate stenosis in the RCA

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for the record, his calcium score came out to

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1,298.

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So again, I think it's great.

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We proceeded, this is a young patient,

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there's no point in bringing him to the ct.

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And then stopping, uh,

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I'm gonna lay out the LAD for you here.

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It's so bright, it's hard to see that calcium,

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but it's just very diseased.

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And then the RCA just in its, uh, you know, see

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that the distal stuff is what I'm most concerned.

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So moderates and then a distal, we did send it

2:08

for C-T-F-F-R here is that, uh, results.

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So a lot of colors.

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You wanna see blue and green, and now we see lots of red.

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So the LED did pan out to be at least pretty good

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to be positive and the RCA as well.

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So the, the second of the series of lesions is

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where it starts to become significant

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and that distal has another focal trans lesional gradient.

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So, yes, uh, say

2:30

that someone asks you look at this like rainbow of dots.

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Uh, what do you worry about?

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Well, you're gonna look for the focal changes.

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Um, this is just a different view here.

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And so, um, this is just a summary image.

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You can interact in their little workstation,

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but this is done right.

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You rarely need it. Um, this is a

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trans lesional gradient at a site of known disease.

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So that I think that's very clearly, uh, correlates well.

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Um, yeah, you do have a borderline lesion in this

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obtuse marginal, but it's

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Not the worst in its distal.

3:00

So I suspect that that would be ignored, uh,

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by the interventionalist.

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And again, you have borderline

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and then, uh, a second lesion

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that makes it definitively positive.

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So let's see what we saw in geographically.

3:14

There's your RCA already have a wire down,

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so they must have not shown us everything,

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but that proximal lesion, not the worst,

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but the mid segment

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does look exactly like it did on the ct.

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And there may be something significant down

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on the distal edge.

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Looks like they proceeded to, to treat.

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I, I can see in the report that an IFR and it was done first

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and it was positive in the R-C-A-P-T-C-A stands

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for percutaneous transluminal coronary angioplasty.

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So they, they're just putting balloons and,

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and stenting some things and ballooning it open.

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Looks like there was a little bit of a complication

3:52

of a dissection that they recognized.

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And it's expected the more calcium you get.

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So in the end, a good result, very good result.

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Um, and now moving on to the left.

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And you can see this is the circumflex.

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There's a wire down already, but there's that proximal

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or osteo LED lesion.

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We were more worried about the mid segments.

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They just investigated.

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They have a wire in the of tooth marginal territory,

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so pre dilating a stenosis, and that's in the LAD.

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So treating exactly where we thought they would.

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So they did some quantitative angiography, some wiring

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looks like complex case.

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And what the final decision was

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that the LAD was not 75% due to the calcified plaque, uh,

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obtuse marginal, they just a lot of small stuff.

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And they called it subtotal,

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99% occlusion slash stenosis in the distal, uh, RCA.

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So, um, treatments, as you can see,

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was successful in the RCA A and they did an atherectomy.

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That's why there was so many images on the LAD

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and put drug looting stents afterward.

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And that did fix the IFR value. So then it was normalized.

5:02

So a great and very complex case in a fairly young patient.

Report

Faculty

Brian Ghoshhajra, MD, MBA, MSCCT

Academic Chief, Cardiovascular Imaging and Associate Chair, Operations Analytics

Massachusetts General Hospital / Harvard Medical School

Tags

Vascular

Coronary arteries

Cardiac CT (SCCT Cat B1 Video Case)

Cardiac

CTA

CT

Angiography