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Hello everyone and, uh, thank you to MRI online, um, for

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the limitation to speak to you about one

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of my favorite topics, which is CT colonography.

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And the title of this talk is, uh,

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screening CT Colonography, a Safe Effective Test.

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And, uh, during this, uh, talk, what I'd like to do is, uh,

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start off by briefly reviewing with you the epidemiology

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of colorectal cancer

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and why it's so important, uh, to screen

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for this mostly preventable malignancy.

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Then we'll, uh, review some of the current guidelines

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for colorectal cancer screening.

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Um, I'll review with you state the art practice of CTC,

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including, um, some of the validation studies,

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and then we'll talk about current patient preparation

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techniques, uh, and, uh, methods for interpretation.

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And I'll end off with, uh,

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discussing briefly the current status

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of reimbursement in the United States.

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Um, and let's get started with, um,

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the global, uh, colorectal cancer rates.

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And it's important to note that this is a common malignancy.

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It's the third most common in men

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and the second most common in women globally.

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So this accounts

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for 1.8 million new colorectal cancer cases each year

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and about 880,000 deaths.

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Look at where the highest rates of colorectal cancer occur.

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Well, in North America, that includes both Canada

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and the United States.

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Australia is a particularly hotspot for colorectal cancer.

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Uh, various sites in Europe, uh,

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South Korea, and then Japan.

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So here's a heat map of, uh, the, uh, incidence rates

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for colorectal cancer.

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And you can see that Australia has a very

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high incidence rate.

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Um, and is it red?

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Everything else that's in orange is also fairly high.

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So you have North America.

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Here's the United States, but also various, uh,

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large portions of, uh, Europe as well.

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In the United States, uh, the

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statistics really parallel globally,

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so it's the third most common malignancy in the second the

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cause of cancer deaths.

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Um, annually we have about 150,000 new cases,

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about 50,000 deaths, um,

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and it represents about 10% of old cancer cases.

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And this, uh, graphic just again, shows you that, uh,

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in the states represents, uh, the third most, uh,

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common malignancy, uh, in men, uh, and in women.

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So in men's, behind prostate and lung

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and women's behind prostate, I mean,

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I'm sorry, breast and lung.

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In terms of estimated deaths, you can see that, uh,

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for men it's third, uh, behind lung and prostate

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and in women's behind breast.

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However, when you consider, uh, men and women together,

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Colorectal cancer actually, uh, counts for

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and represents the second most common cause of women deaths.

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Again, the lifetime risk

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for developing colorectal cancer is about 5%, uh,

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which represents one in 20 individuals.

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Lifetime risk for dying from colorectal cancer is

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about percent.

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Therein in this last line is important, which is

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that majority, 70% occur in average patients

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who have risk.