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Case: Applying a Systematic Approach to Image Review

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0:00

Okay, so let's look at another case

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and hopefully this is one that I've selected

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that has read the textbook.

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So I'm gonna start with my rotating mit,

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we'll invert it in Arma

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and then adjust the levels so

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that I'm just seeing outline of the patient's skin.

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That looks pretty good. Now we're gonna give our rotating

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MIP a spin and we're seeing physiological uptake,

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lacrimal glands, Sali glands a bit in the head and neck.

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That looks fine. Some mild uptake in the

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thorax is probably reactive.

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Lymphadenopathy, liver, spleen, kidneys,

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bowel coming all the way down

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through our ureters to the bladder.

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But what we are seeing here is something inferior

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to the bladder, which is exactly where the prostate is.

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And this is a patient who saw us prior

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to radiotherapy treatment.

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So this is where the pro,

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we're gonna be looking very carefully for

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that primary prostate cancer.

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But while we're here on this rotating mip, I'm also looking

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for some dots in the pelvis.

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Are there lymph nodes I need to scrutinize?

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Is anything jumping out?

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Is there potentially skeletal lesions somewhere else in the

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field of view that I need to be worried about?

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So let's now jump into our axial fuse

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and I'm just gonna make that a little bit bigger.

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There we go. So here, um, we're going to jump

1:05

to the, the pelvis.

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So coming down 'cause

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with our tumor nose metastasis are the findings we really

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want to kind of hone in, um, on the primary tumor first

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and bringing in, we're just gonna put in a second layout.

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I'll put in my CT

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and then come down we can see

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that the patient's had intravenous contrast for delineation

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of the urinary tract, which is very helpful.

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And then coming down, we'll zoom this up a little bit

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and scroll it to the middle.

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Um, this patient actually has some

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high density material here.

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This is hydrogel to separate the rectum from the prostate

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for radiotherapy planning.

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And then these bright things.

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So there should be 3 1 2, 3 are radiotherapy seeds.

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So this patient is being planned for radiotherapy.

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So I'm treating a little bit.

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I know that this patient is um, already coming

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to us already a therapy with a diagnosis of prostate cancer.

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So scrolling back down again, now that we know

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that they've got their fiducials

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and their hydrogel and situ.

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So this is a patient who probably has comparison imaging.

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So I'll have that up side by side.

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And what I'm looking for is this intense uptake

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as opposed to background.

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And you can get some heterogeneous uptake

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elsewhere in the prostate.

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And we'll have a look at some benign patterns

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in the upcoming section.

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And this is probably within normal limits

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but this kind of bright white that is not.

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And this is corresponding pretty much exactly to

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what we saw in our rotating mi.

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We'll just adjust that again

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and bring down our levels so we can see

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that this heterogeneous uptake more to the left

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of the midline is corresponding to this intense uptake, um,

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through the prostate.

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So here is the prostate base near the bladder coming down,

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so to the mid gland to the apex.

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So the left hemi gland involving the peripheral zone

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and a lot of through the central gland as well.

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So this is quite a large tumor.

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After that I'm going to be considering um,

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our pelvic lymph nodes

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and looking very closely here at the pelvic sidewalls

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to look for focal

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Uptake. And

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I'll pick one side, I often go left first,

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then I follow up the ureters coming up

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and there's a ureter here just crossing over

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and then it, taking it out to the inguinal region

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and then up again then reviewing the internal ILI X,

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knowing that that's the ureter.

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Then going in, then repeating it backwards on the other

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side, internal iliacs up to the pelvic sidewall

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and then going up and down, checking that out

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and then picking up the external iliac vessels

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and coming all the way back to the retroperitoneum.

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And then really concentrating my eye here in the

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retroperitoneum as I move upwards

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and then using that as my landmark

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because lymph nodes like to follow vessels.

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Um, and so here we go.

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We've got our ganglia here and then up into the mediastinum

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and then I'm going to re-review those mildly avid lymph

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nodes and agree, yeah, there's a little bit of uptake.

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I'll mention them in my report

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but downplay them as reactive and go up.

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And again, we've got our little, we've got a little bit

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of um, mildly avid fibro scarring in the lungs.

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And then just looking for our ELLA ganglia,

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which are probably somewhere in here.

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And then going through systematically looking

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for our M staging.

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And I do the abdomen first,

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turning the avidity on the liver and spleen up.

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I'll jaw by quadrants really look at this liver through here

4:13

as well and I can't, I'll see if I can adjust that liver up.

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There we go. So that's what we really wanna be looking

4:18

for enough to see through the liver here on there, on there

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to see if there's any, um, lesions through it.

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And then also as we saw

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with the video is turning on our lung windows, moving up

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and down and just systematically drilling by quadrant

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and then using our um,

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MI tool if you have it on your viewer

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to increase your sensitivity for nodules.

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It's a couple little peric things here but no avidity

4:45

and then going through the bones

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and the sagittals are great for that.

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Now interestingly, this patient does have an abnormality in

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the bones here and it is mildly avid.

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There's a wedge compression fracture at,

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um, I'd count from the top.

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So it looks like near the thoraco lumbar junction.

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Um, that doesn't have too much uptake.

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But in saying that, the referrals will ask me,

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do you think this is a pathological fracture?

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And usually the answer will be no if it has this typical

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anterior compression fracture morphology

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without significant uptake.

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But keep in mind that recent fractures can be mildly avid.

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And so I'm looking for patterns.

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And if there was no other sites

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of skeletal metastatic disease,

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this would be unlikely with my fusion.

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I'd be looking at bone windows, reconstructing the data

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and going through closely checking every bone, um,

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and then reading the total body pet

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with a systematic reproach, checking head

5:29

and neck, thorax, abdomen, pelvis,

5:32

and skeleton to ensure there are no clinically significant

5:35

incidental findings.

Report

Note

Faculty

Sally Ayesa, MD, MSc, MBBS, FRANZCR, FAANMS

Lecturer, Radiologist & Nuclear Medicine Specialist

University of Sydney & NSW Health

Tags

Prostate/seminal vesicles

PET/CT PSMA

Oncologic Imaging

Nuclear Medicine

Neoplastic

Genitourinary (GU)

Body