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Severe Calcified/Mixed Plaque

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Okay, this next case is a 67 year

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old woman who has a history of chest pain who came

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in for coronary CT evaluation in this patient

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and also having severe disease.

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So we'll start again with the axial images.

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And as we go down.

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We know this is this may be tough to pick up on axial. But

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you know over time I think after reading all these CTS

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you'll start to recognize.

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the connection between the LED and the

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circumflex and the cusp is

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not normal here. You're not really

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seeing a good left Main.

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And so this is concerning for

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a left main stenosis. Now the

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big thing that you have to think about.

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As another possibility here is that there's some motion artifact

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that's blurring this region and that can absolutely simulate

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us stenosis.

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If you look around at the neighboring structures, though,

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usually if you have a blurring artifact it's going to affect.

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other structures as well

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and you can see that the wall of the aorta is

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very clear.

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Same with the left atrium same with the LED.

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So maybe this isn't blurring artifact after all

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so we'll keep our eye on that subsequent CPR images.

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Now if we continue down the LED, I'm

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going to zoom up. It's kind of a small vessel

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on this patient.

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You're gonna see and this is a normal

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looking very proximal idea and they may right away get into this calcified plaque,

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but we do see a fair bit of contrast getting

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by and it doesn't look like there's a significant stenosis.

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And then more distally.

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We see even more calcified black.

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But again with some decent looking contrast movement.

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Now here's where we get into trouble with cardiac CT.

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And and that is when we have heavily calcified lesions

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in small vessels. And this is a good example. You can

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see this diagonal Branch here. We basically have

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a lumen and calcium and it's honestly hard to tell

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where one begins in the other ends.

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And then beyond that you see that you lose the

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Lumen and there's this Gap and then you

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get into the more distal diagonal Branch here.

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So sometimes we can use the

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Calcium score to kind of help us to

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sort of Orient ourselves to where the diseases. So in

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this case, here's the corresponding calcium score for

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this region this patient and sure enough. You can see that wow. There's

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a lot of calcium.

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So this patient has a really severe disease and I mentioned some of

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the early videos. We were talking about indications for coronary CT that

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heavily calcified

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Lesions is is where coronary CTS

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accuracy really kind of falls down. This is

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where coronary CT has a lot of trouble now. There is

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some Hope on the horizon that these some of

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the newer scanners in particular the photon counting

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scanners and some of the other high-resolution type

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scanners that are out there may be

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able to help with this problem. But for the

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majority of the current generation scanners out there, this is

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not an easy problem to fix.

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So, how do you deal with it? Well, what you want to do

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is you want to go to your

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sharp kernel reconstructions. So that's

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what we see here on the right. They're always a little bit more noisy, but they're

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gonna give you slightly better definition of the edges of

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our calcified plaque.

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And then you kind of just do your best.

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If you see Lumen like you do in this case.

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And it looks like it's a fairly uninterrupted column

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of contrast then usually I'm gonna call that mild.

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When I get down further though, and I see that it's hard

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for me to separate the Lumen and the plaque.

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or further Downstream right here where I

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see that the diagonal comes off and then

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I really have

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Honestly, I I can't tell if there's Lumen there or if there's calcified

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plaque. It looks to me like it may be

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a hundred percent calcified black.

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This is where we usually give the caveat and

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the caveat is heavily calcified stenosis,

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you know obscures vessel

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Lumen, probably 70% or greater, but maybe over

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underestimated by a CT and that's sort of a standard

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tagline that unfortunately we have to use sometimes

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with these lesions that are really severely calcified

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on coronary CT. This is the main

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limitation of coronary CT in terms of accuracy when

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you have tons and tons of calcified plaque. So if

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we follow the vessel further, you can see we have this

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big calcified lesion here.

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Then we go further a little bit of narrowing

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here, which looks like this probably secondary to some non-calify

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black and then here we kind of lose the

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vessel and that comes back again. So that makes you wonder

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again if there's some non-calify black in that vessel.

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Let's look at the other vessels if we look at the RCA.

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Just notice here how much better with the sharp kernel

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you can see the calcium then

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you can on their standard kernel on the right.

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That's that's why it's particularly useful.

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Same thing here standard kernel, it looks kind

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of like a blob of calcium here. You can actually see some definition. There's

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two calcified plaques next to each other rather than

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one single calcified plaque.

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And then as we go down further distally in the

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RCA, I think can appreciate that. There's a fair bit of calcium, but

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there's no significance stenosis except

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for perhaps right here at the origin

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of PDA. There might be some plural narrowing.

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You see that this is the plb continuation right

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here.

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And right there, let me see some mixed plaque

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both calcium and non calcified black.

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That's causing some narrowing of that PDA origin.

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So we'll have to keep our eye on that on some of the

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reconstructions as well.

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And then to close it out. Let's take a look at the circumflex.

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You can see this is a pretty dominant right corner artery. So

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I don't expect a big circumflex and sure

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enough. That's the case. You can see it's quite a small vessel here.

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Comes down. There's an obtuse marginal Branch there from

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the high circumflex and then kind of comes over.

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Here and just kind of Peters out into the sort of

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lateral aspect of the LV wall.

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Okay, so let's take a look at the LED.

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here's our CPR reconstruction and

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Unfortunately, this is an example of a CPR

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that doesn't always go exactly where

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you need it to go. And in this case, it didn't quite follow the LED beyond

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the mid segment here.

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It looks like it picked up a vein and then stopped so we

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can work with that because we know how to use our nprs and I

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mentioned that as one of the reasons that's really important to be familiar with

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how to use the nprs in these cases. So again, we can

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see what looks like mild disease proximally and then when we

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get past this diagonal Branch, it looks to me like there's

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stenosis in the diagonal itself as well as

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some calcified black and non-calify black and led beyond the

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diagonal. It looks concerning for significant stenosis.

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But again right here, I'd have to say that there's severe calcification

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in a small vessel that obscures Lumen

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visualization and suggest

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70% or greater stenosis, but maybe over underestimated by

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coronary CT do the heavy calcified

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plaque burden that's sort of the usual phrasing that

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we use.

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Now one of the thing that we wanted to remember to keep

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an eye on was the left mean and so here is the

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left main here.

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And again, it doesn't look good. It

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looks like there's a severe stenosis most likely

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From noncosified Plaque.

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whenever you're using CPR though, you always have to be a little

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bit careful because sometimes

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the CPR itself can be a little bit off

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center line and that can give you a fake out. So let's

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check out. Let's take a look at some other views.

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Circumflex, this seems to be a pretty good Center Line

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and it still shows that same stenosis or

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a suspected stenosis in the left main. So

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I think this is going to end up being real and then

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if we go to our short axis reconstructions,

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That sort of a little closer to kind of

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the ground truth. I think and sure enough you

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can see this stenosis. So this patient has what looks like

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a severe left means stenosis. That's a big deal that puts

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her into the catarans for bee category and that type

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of patient may need to get a cabbage to

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deal with this severe disease.

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We can also on this short axis reconstruction take a

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look at the Led disease. So proximately here it

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looks kind of mild but then when we get Beyond this diagonal Branch,

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that's where we get into trouble.

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Small vessel big calcification it's kind of

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tough for us to tell exactly what's going on there. But I

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would generally read that is suspected, you know,

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significant stenosis may be overestimated or underestimated

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because of the heavy calcification.

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So for this patient, thankfully we have a calf follow-up

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which will take a look at next.

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So here's the calf in this patient.

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And first I want to focus on the left mean disease. So here's

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an Arrow showing us this stenosis in the left main that we

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saw on both. Our curve planner reconstruction images are

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short axis images and the axial images.

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And sure enough.

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There's a high grade stenosis of the left mean in

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this patient. So this is this is a big deal.

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And this is something that would need to be treated in

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general with with cabbage.

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Now what about that led and the diagonal

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branches? Well when you look at the calf.

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at the Led in the diagonal

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here's the best view I could find from their cath images.

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You can see the diagonal here actually looks okay surprisingly which

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for us it didn't look that great. So

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that's probably a function of our calcium faking us

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out and then here in the LED though. We do see that

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there's they did call serial stenosis in the

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mid LED after the diagonal branch is how they phrased it.

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And they said 80% or greater. As you can see that there's a sort

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of a fuzzy stenosis here right after the diagonal origin and

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then a fuzzy stenosis here and my best

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guess is that these correspond to these highly calcified areas of

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plaque in the mid LED beyond that diagonal that again,

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we're tough for us to evaluate but looks like they did correspond to

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some severe lesions.

Report

Faculty

Stefan Loy Zimmerman, MD

Associate Professor of Radiology and Radiological Science

Johns Hopkins Medicine Department of Radiology and Radiological Science

Tags

Vascular

Cardiac CT (SCCT Cat B1 Video Case)

Cardiac

CT

Acquired/Developmental