0:01

<v ->And the next case here is, let's take a look.

0:07

It's also a classic case.

0:08

It's a 35 year old female.

0:12

And what we can see is also epiphyseal,

0:17

and metaphyseal bone lesion

0:23

with margin that is well defined.

0:31

We have some cortico thinning here, and erosion,

0:39

a little bit of edema outside the lesion

0:42

that we also can see with T1.

0:46

We don't have any sclerotic border,

0:50

that's characteristic of this non-aggressive

0:55

Giant Cell Tumor.

0:57

So, I showed two types of Giant Cell Tumor.

1:01

This one is non-aggressive,

1:04

and the one at the radius is aggressive.

1:06

And you know what?

1:07

The prognosis of both aggressive and non-aggressive,

1:11

they don't change a lot.

1:14

Doesn't matter actually for the prognosis,

1:18

if the the type of the lesion.

1:21

So, here we can see that the.

1:25

And even if they are benign,

1:28

they can do a metastasis to the lung,

1:31

and nobody knows why,

1:33

the radio tumor, the tumor of the radius,

1:36

the Giant Cell Tumor is typically

1:39

can metastasize to the lung, even with his benign pattern.

1:49

So, this is the classic type, Donald.

1:52

<v ->Yeah, this is interesting to me,

1:54

just to point out something about distribution.

1:58

You know, we always talk about Giant Cell Tumors

2:01

as being epiphyseal lesions,

2:03

and we think of them as extending down

2:06

to the subchondral bone.

2:08

But as you know, there are reports of Giant Cell Tumors

2:12

in the immature skeleton, where they are metaphyseal,

2:16

and they then as the physis closes,

2:19

they extend into the epiphysis,

2:21

and eventually reach the subchondral bone.

2:24

So, it'd be interesting to know perhaps

2:27

what this might have looked like when the physis was open.

2:31

Was this in the metaphysis?

2:33

And is it subsequently grown down into the epiphysis

2:37

with closure of the growth plate?

2:39

Very nice case.