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Non-visualization of Suspected Abnormality

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Challenge number five, the disappearing lesion.

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So this is a lesion like the one I just showed you.

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So these are patients who have a lesion

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that shows on the diagnostic study,

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but when you come to biopsy it,

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you can't find a target to biopsy.

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And this is always a little anxiety provoking, both

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for the patients and for the radiologist when this happens,

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because you wonder if it's there

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and you're just not seeing it

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and you don't wanna miss a cancer, et cetera, et cetera.

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One thing that's really important in this case is you need

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to warn the patients this might happen

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at the time of consent.

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Um, it happens I would say in about 10%

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of our cases, roughly.

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Um, so it's not an insignificant risk as such.

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Um, I tell patients sometimes these things don't light up

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when we come to biopsy them.

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If we don't see it, then we can't biopsy it.

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Um, I explain to them we would be doing a follow-up scan in

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that situation, um,

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but that if we stop the study in the middle, that's why.

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And they just need to know that it's,

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it makes it much less distressing for them.

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And a surprise, the first thing you need

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to do if you don't see the lesion is make sure

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that there has been an adequate contrast injection.

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If the contrast hasn't got into that patient,

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if it's all infiltrated into their arm,

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you ain't gonna see that lesion.

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So look at the heart, look at the blood vessels, make sure

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that you have contrast on the post gadolinium image.

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The next thing that can happen, I'm gonna show a diagram

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for this in a minute, is the breast can be over compressed

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if you squeeze that breast too firmly.

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You want it firm enough to be able to fixate it,

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but not enough so that you're basically stopping the blood

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or the contrast coming in.

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If you think that it is over compressed,

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get the technologist to release

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the compression a little bit.

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You know, you assuming you have adequate contrast in there,

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and then take another scan.

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Sometimes it just needs an, uh, an extra couple of images

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to do and some subtractions to be able to see the lesion.

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And I will always take some additional imaging further out

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and see whether it turns up the more

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progressive type of flow.

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Um, generally speaking, the coils that you are using

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for the biopsies do not have as many channels,

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so they're not as high quality, high resolution

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as the regular diagnostic coils.

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So, and the breast is more compressed,

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it's positioned differently

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and it can be quite challenging sometimes to just sort

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of work out the anatomy.

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Um, I, my rule of thumb is if I see anything that lights up,

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it enhances in the place where I was concerned

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that corresponds to the lesion, I will biopsy it.

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I do not say, well, you know, it's not enhancing as much

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as it did on the diagnostic study.

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Let's leave it alone because, um,

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it often does not enhance as well.

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And then finally, if none of these things work,

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you're gonna stop the exam, reassure the patient,

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but you should repeat that exam in three to six months.

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Um, studies have shown in this situation

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that there is a five to 10% false negative

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Rate. For

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whatever reason it didn't enhance on

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that study, but it is a real lesion.

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So how do we know if a breast is over compressed?

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Well, um, don't laugh. Well, you can't laugh.

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Um, but this is how I do it.

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So this is how you test stake by feeling it.

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So how tense at stake feels, how dense

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that stake feels is how well done it is.

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And you position your hand, like here,

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you're pressing on your thena eminence,

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and you move your thumb across various fingers.

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And as you move it from the first finger over

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to the fifth finger, it's an in your,

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you'll notice your thena, eminence

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and I, I know that you're all trying it at home right now,

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um, will go from being, uh, medium rare to well done.

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Well, we want the breast to be medium rare.

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So after the technologist has positioned the patient,

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I will stick my finger through the grid, obviously with no,

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um, cleaning up done at that point before we start the scan.

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And I will prod her breast to see if it feels medium rare.

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If it feels well done, it's too tight.

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If it feels rare, then that breast is, is not tight enough.

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That grid is not tight enough on the breast,

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and the breast is going to move

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and push away from me when I try and biopsy.

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Faculty

Petra J Lewis, MBBS

Professor of Radiology and OBGYN

Dartmouth-Hitchcock Medical Center & Geisel School of Medicine at Dartmouth

Tags

Women's Health

Non-infectious Inflammatory

Neoplastic

MRI

Idiopathic

Diagnosis & Staging

Breast