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Wk 5, Case 5 - Review

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This is Pediatrics week 5 case number five. The

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diagnosis under consideration is inflammatory bowel disease

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and we have Mr. Enterography, which

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is the gold standard for evaluation on Imaging. Of

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course as a corollary, the gastroenterologist will

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perform colonoscopy or maybe even EGD and

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do direct visualization and

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biopsy sampling of the mucosa.

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On Mr. Imaging what we expect to see

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if inflammatory bowel disease is indeed present is

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free fluid indicating inflammation in

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the abdomen. We expect to see bowel wall thickening whether

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it be spot lesions and the ilium and colon

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or even the rectum.

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or continuous involvement

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and then in severe cases, we might see fistulization

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of the bowel to other structures even to

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the skin and abscess in a late

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complication and then there's also the possibility

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of perianal disease which is typically evaluated separately

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on an MR pelvis. We're going to focus on the bowel here

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on this case. I've got T2 weighted.

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Coronal Imaging and you can see there is fluid in the bowel. This

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patient has ingested positive contrast in addition to

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us giving IV contrast on later Imaging sequences. And

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as we scroll through we can see the majority of

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the loops of small bowel have a normal appearance of the bow wall.

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This isn't asymmetrically thickened. It doesn't

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look abnormally collapsed. This is pretty typical. We're not

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too worried about this Bell.

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First I want to go over and look at these Loops, but

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then I want to look at the colon and cecum.

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And here's the cecum here. And this looks like a little mild wall

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thickening. Here's the iliocecal valve.

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Don't be confused by the leaflets of

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the valve appearing in large. That's typical. What we're

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more interested in is what does the terminal ileum? Just prior to

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that ileocal valve look like and it looks a little thickened and

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as we scroll backwards we can see some abnormal

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thickening of this terminal ilium, so I'm going to magnify this.

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Just so that we can drive this point home. So we're very much

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looking carefully at the right lower quadrant. Look

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at the thickness of the bowel wall. So this is

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normal colonic bowel wall.

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Look at the sharp thin lines.

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That's appropriate. However

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If you look over here, this wall is

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quite thickened on both sides.

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And this is focal inflammation of

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the terminal ileum. And if I were to

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scroll over over by the cecum, you would see the same appearance.

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So we've got asymmetric partial involvement

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of the terminal ileum. We've got thickening you

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can even see the diameter of the Lumen his tapered

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dramatically from here down to here and

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then of course at the level of the insertion

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on the CM, there's a little bit of thickening of the

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proximal colon.

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Let's go ahead and look at a post contrast Imaging sequence.

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just to see if there is

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Any enhancement?

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And here we can see.

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There's pretty uniform enhancement of the bow

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wall.

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and the

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colon is very full of stool which could indicate

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some level of dysmotility, but you can

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see that the bow wall here.

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Over in the left Hemi abdomen is roughly enhancing as

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much as it is here at this thickened area of the terminal ilium. So

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what that suggests if you see thickening of

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the wall, but not particularly hyper enhancement is

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this maybe chronic inflammatory bowel

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changes without acute exacerbation.

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So once that thickening occurs, it'll be

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there even in between a cute episodes that are

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so called flares of the inflammatory bowel disease.

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This patient turned out to have Crohn's disease but enhancement

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can help you to distinguish between the acute

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and a chronic appearance of the disease. That's

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the end of the case.

Report

EXAM: MRI Small Bowel without and with IV Contrast

INDICATION: 9-year-old female with several weeks of abdominal pain.

TECHNIQUE: MR imaging was performed utilizing multiple pulse sequences both before and after the administration of IV contrast.

FINDINGS:

The lung bases appear unremarkable.

The liver is normal in size and contour. There are no cystic or solid intrahepatic lesions identified. The gallbladder is unremarkable without signs of acute cholecystitis. Negative for intrahepatic or hepatic biliary ductal dilations. Negative for calculi.

The spleen and pancreas are unremarkable in appearance.

The kidneys are normal in size and appearance bilaterally. Negative for hydronephrosis or gross urolithiasis. The bladder is fluid-filled but otherwise unremarkable.

There are no dilated loops of small or large bowel to suggest obstruction. There is moderate to large stool burden within the entire colon, as well as the rectum. There is a ~5 cm segment of distal ileum with wall thickening up to the terminal ileum and additional hyperenhancement and adjacent mesenteric fat stranding. There are several loops of small bowel that are not fluid filled and therefore these are limited in evaluation. The remainder of the large and small bowel is unremarkable in appearance. Negative for stricture, ulceration, or fistulization.

The abdominal wall is unremarkable. The abdominal aorta is normal in course and caliber. The IVC and portal venous vasculature are unremarkable. There are scattered enlarged right lower quadrant lymph nodes which are likely reactive in nature.

There is trace intra-abdominal free fluid visualized predominantly within the right lower quadrant. Negative for pneumoperitoneum. Negative for acute bony abnormalities.

IMPRESSIONS:

1. 5 cm segment of terminal ileum with bowel wall thickening and hyperenhancement, as well as mesenteric fat stranding, consistent with active inflammatory bowel disease. Negative for stricture or fistula.
2. Trace right lower quadrant ascites and scattered enlarged mesenteric lymph nodes, likely reactive.
3. Moderate to large stool burden throughout the colon and rectum.

Case Discussion

Faculty

Brandon P Brown, MD, MA, FAAP

Director of Fetal and Perinatal Imaging

Indiana University School of Medicine

Tags

Pediatrics

Nuclear Medicine

MRI

Gastrointestinal (GI)