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Wk 5, Case 2 - Review

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This is Pediatrics week 5 case 2 and

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our diagnosis under consideration is pancreatitis. This

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is a teenage patient with an MRI.

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MRI wouldn't be the first Diagnostic Imaging

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to perform on a patient with suspected pancreatitis,

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but

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It offers a lot of value especially for

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some of the rarer causes of pancreatitis, which we see in

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children. So initially perhaps an ultrasound

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right upper quadrant ultrasound or maybe a

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CT scan might have identified some of

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the concerning features and MRI can add some

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specificity.

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To our diagnosis in children in addition

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to traumatic pancreatitis and congenital

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causes of pancreatitis and

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maybe even for older teenagers alcohol-induced pancreatitis. There's

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also the category of autoimmune pancreatitis, which

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is

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something that we have to be mindful of.

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and it's still not the most common cause

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of pancreatitis, but

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relatively speaking. It is a more significant

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cause in the Pediatric population partly because many of

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the cases that we see in the adult world are

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less common in children such as alcoholism.

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So here's an MRI sequence, we've

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got an axial fluid sensitive image here a

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T2 weighted image. And as I scroll down through

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you can see that the liver appears pretty normal that portal

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Triads were coming into the port of hepatis. We've got a little fluid in

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our stomach and here's the spleen. We're just getting

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the top of the left kidney and we're coming down to the epigastrium sure

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enough. Here's the pancreas coming across the midline. The

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first thing we notice about that pancreas is how dark it is. We

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don't expect to see the pancreas this

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dark relative to the liver.

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And as we come around the other thing, I hope you'll notice about the

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pancreas is how featureless the surface Contour is

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it looks bulging swollen. Some

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people might even say sausage like we do see

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the pancreatic duct coming along the center

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of the body, but it's not particularly dilated. So

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this isn't an obstructive pancreatitis and

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this isn't a chronic pancreatitis where

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we get that.

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Progressive enlargement after repeated cases of

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pancreatitis enlargement of the duct but we do see a

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dark edematous swollen pancreas

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no significant ductal enlargement and the

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signal intensity is low. Let's go ahead and look

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at the same region after the administration of IV

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contrast.

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Here's our post contrast image and notice that in

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this very early post contrast image arterial phase.

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Look at the cortex of those kidneys and the aorta.

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We really aren't seeing much enhancement.

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That's not quite right the pancreas loves doing hands. Let's

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give it a little bit more time and look after a minute.

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So now we're more of a Venus phase again, not

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all that much enhancement here. You can see the splenic vein

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coming over and joining with the mesenteric and giving us the portal.

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And the pancreas is just not that bright. Let's go ahead and give

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it a two-minute delay and here is

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Just a tiny bit of enhancement. So we're getting slow

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Progressive enhancement of the pancreatic

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parenchyma. Not as much as is expected and

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not as quickly as is expected. So all of

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these findings put together are very suggestive of autoimmune

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pancreatitis and just to take you back to the fluid sensitive

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sequence. Here's the t2. There's a

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little bit of free fluid you can see in the Perry hepatic

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region over here and maybe a little

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bit on the left percolic gutter Perry splenic region, but

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look at the pancreas, it is not surrounded by a lot

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of Perry pancreatic fluid like you might expect to see if there

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had been some sort of a traumatic.

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or acute pancreatitis, so

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These are some of the features to be on the lookout for with autoimmune

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causes.

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Low, signal intensity poor initial enhancement swollen

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appearance almost sausage, like and

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lack of significant dilatation of the main pancreatic duct.

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That's the end of the case.

Report

EXAM: MRI Cholangiogram MRCP without and with Contrast

INDICATION: 14-year-old male with history of elevated bilirubin as well as pancreatic and liver enzymes.

TECHNIQUE: MR imaging was performed utilizing multiple pulse sequences both before and after the administration of IV contrast, using an MRCP protocol. The pelvis was not included.

FINDINGS:

MRI Abdomen:

The liver size and contour are normal without evidence of fibrosis. There is no hepatic mass or steatosis. There is patent hepatic arterial anatomy, as well as patent portal and hepatic veins. The SMV and splenic veins are patent.

The pancreas is diffusely enlarged with peripancreatic edema. There are segmental areas of decreased enhancement within the pancreatic body and neck, which spare the head and tail. There is subtle delayed capsular enhancement (capsule-rim sign). The common bile duct and pancreatic duct are mildly dilated, with narrowing and caliber change at the pancreatic head.

Stable splenomegaly, measuring up to 15 cm. The adrenal glands are of normal size and morphology. Stable left renal cyst. No hydronephrosis. No evidence of dilated bowel or obstruction. No abnormal areas of contrast enhancement.

The abdominal aorta is normal in caliber, without aneurysmal dilatation. The celiac, splenic, and superior mesenteric arteries are patent. There is no lymphadenopathy.

MRCP:

There is no gallbladder wall thickening or calculi. The common bile duct is mildly dilated and measures up to 4.5 mm. The pancreatic duct is mildly enlarged. Both the pancreatic duct and common bile duct sharply taper at the pancreatic head. There is normal anatomy without pancreas divisum.

IMPRESSIONS:

1. Diffusely enlarged pancreas with peripancreatic edema consistent with pancreatitis. There are findings which raise concern that this may represent autoimmune pancreatitis.
2. Stable dilatation of the common bile duct measuring up to 4.5 mm. Question small linear filling defect within the common bile duct which may represent biliary sludge, less likely stones.

Case Discussion

Faculty

Brandon P Brown, MD, MA, FAAP

Director of Fetal and Perinatal Imaging

Indiana University School of Medicine

Tags

Pediatrics

Pancreas

Nuclear Medicine

MRI

Gastrointestinal (GI)