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Wk 3, Case 4 - Review

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This is Pediatrics case 3 week 4

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and the diagnosis were considering is osteomyelitis. So

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as you would expect we're going to look at an MR

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scan.

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Osteomyelitis can be detected on radiograph but

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it's more difficult and it's typically seen when it's

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a more advanced as a disease process. So

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it may involve destruction of the trabecular bone loosen

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sees within the medullary space of the bone or periosteal

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reaction along the cortex of the bone in advanced

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cases. There can be outright bone destruction.

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Certainly secondary effects of infections such as septic arthritis

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and others can be detected on radiograph.

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However, MRI is the gold standard and

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we're going to look at some.

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pre and post contrast Imaging now it turns out

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that

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Contrast is not required to evaluate

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for osteomyelitis with

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MRI. And if you see normal bone

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marrow signal on a non-contrasted MRI, the literature

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suggests. There's no reason to add contrast normal scan

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pre contrast. You can be done. However, if

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you're concerned for complications of

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osteomyelitis, if you want to evaluate for example

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for synovitis in the joint space or

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interosseous abscess or these types of

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sub periosteopsis contrast can offer some

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advantages so

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It can be a useful adjunct particularly in cases where

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there are already signs of disease on the pre contrast Imaging.

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So I'm going to scroll through this coronal image. This is

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a fat saturated image so the

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normal bright T1 signal isn't there but you can see

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already that there's some abnormality in the distal metaphysical femur.

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There's some abnormal bone marrow signal and there's a focal lesion

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right at the level of the fisces itself.

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Maybe it's even involving some of

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the epiphysis I'm going to

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pull up the

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post contrast images of this same region

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And after the administration of contrast for one

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thing we can see that there is enhancement

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of the synovium for another

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thing. We can see a lot of enhancement in this same

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region. This focal space has a rim enhancing appearance

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centrally no enhancement. Now, we're very

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concerned about abscess and it appears to extend into the

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fisces and when we scroll down we can see it even

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touches the epiphysis a little bit. This is a trans visual interosseous

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abscess. There's bone marrow signal changes compatible

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with osteomyelitis if we look over at the sagittal View,

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Here, we've got a nice depiction of

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septic arthritis with this joint space filled with

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Fusion and the synovial lining brightly enhancing

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also some thickening of the synovium. And

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here's that focal region right at the

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level of the fysis where you can see that there's a central

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portion where fluid has accumulated and the

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contrast agent is not able to reach so you can see the Rind of

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this extending here with this Central area of non-enhancing

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fluid the abscess

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fluid itself.

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so this patient has

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several complicating features of osteomyelitis certainly needs

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to be under a surgeon's care. And the last

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thing I'll show is the axial appearance

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of this same disease process, which can be nice

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to give us a sense of the posterior compartment of the knee. This

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is below the knee and then as we come up,

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Above at the level of the femur we can see our

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area of interest posteriorly and we can see

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the enhancement of all of the synovium and retinaculum

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quite brightly.

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That's the end of the case.

Report

EXAM: MRI Right Knee without and with IV Contrast

INDICATION: 10-year-old female with fever

TECHNIQUE: MR imaging was performed utilizing multiple pulse sequences both before and after the administration of IV contrast.

FINDINGS:

The medial and lateral menisci are intact. The anterior and posterior cruciate ligaments are intact.

The medial collateral ligament is intact. The iliotibial band, mid third lateral capsular ligament, fibular collateral ligament, biceps femoris tendon and conjoined tendon are intact.

The quadriceps tendon and patella ligament are intact. The articular cartilage surfaces are intact.

There is a large joint effusion with marked synovial enhancement, compatible with synovitis.

There is extensive abnormal marrow signal in the distal femoral metaphysis extending to the growth plate, compatible with marrow edema. On postcontrast sequences, the same area demonstrates enhancement.

The is a 12x9x12 mm rim-enhancing lesion located along the superior and medial aspect of the distal femoral physis. The cortical bone posterior to this lesion is thinned, indicating bone destruction. The location of the lesion correlates with the focal lucency seen in a corresponding location on the knee radiograph. The marrow signal of the epiphysis is otherwise normal, with only minimal edema, likely reactive.

There is edema in the surrounding musculature and soft tissues of the posterior knee, compatible with cellulitis and myositis.

IMPRESSIONS:

Distal femoral metaphyseal osteomyelitis. Small abscess along the posteromedial aspect of the physis. The infection does not appear to have spread to the epiphysis. Large enhancing joint effusion concerning for septic arthritis.

Case Discussion

Faculty

Brandon P Brown, MD, MA, FAAP

Director of Fetal and Perinatal Imaging

Indiana University School of Medicine

Tags

Pediatrics

Nuclear Medicine

MSK

MRI