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Case Review: 82 yr old with progressive gait disturbance and memory loss

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Is an 82 year old female that, that came to me with, uh,

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concern for M P H and basically she had progressive gait disturbances, uh, and,

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uh, memory issues. And as you can see, her ventricles are enlarged. Um, and,

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and it is a little bit out of proportion of the degree of her volume loss

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overall. Um,

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you can see she does not have any aqueduct stenosis and her collosal angle is

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narrow, suggesting hydrocephalus rather than just volume loss in this case. Um,

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so we did do a, uh, a flow study, um, and essentially the, the first thing,

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I always look at these axial flow studies.

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I wanna see at least that there's two and fro flow through the aqueduct on the

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initial image acquisition. So I wanna see, um, you know, basically the, the,

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the bright flow jet and then the reverse flow jet giving me sort of a dark

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signal as it as it goes backwards. Um, and essentially you're gonna have, um,

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forward flow and backwards flow.

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The stroke volume is actually the flow in one direction,

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not the flow in both directions. So, um,

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the stroke volume in this patient is around, uh,

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or just a little over a hundred microliters.

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It's very common to see patients have slightly more forward flow than

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backwards flow because they're making C S F, so you presume that, you know,

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they're secreting some out of the brain to go to the arachnoid granulation and

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be reabsorbed. So having a slightly higher forward volume is, is typical,

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but if there's a big discrepancy between forward and backward volume,

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I tend to not really believe the stroke volume. So this is a, a,

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a case where technically the stroke volume was telling us that this patient

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probably had N P H. Um, the flow volume was not that impressive,

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though it was only six mls per minute. Um, whereas, you know,

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24 has been more closely correlated with, with patients who have N P H.

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That being said, you know,

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we felt very strongly about this patient potentially having N P H and we did do,

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uh, high volume LP and this patient recovered dramatically and, and did very,

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very well with a shunt. Um,

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so it just goes to show you the flow study may not always give you the answer.

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Um, it really is meant to mostly predict shunt responsiveness rather than really

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diagnose N P H.

Report

Faculty

Jeffrey Scott Pannell, MD

Director of Neurointerventional Surgery

University of California San Diego

Tags

Spine

Neuroradiology

MRI

Interventional

Idiopathic

Brain