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Challenging Breast Cases - Case 6

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Okay, moving on to the next case.

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okay, so this is a

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These images here from a 38 year old woman who noticed a

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right breast lump in the shower about a month ago

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a little bit achy, but not particularly painful

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or Tender on physical exam.

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the

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nurse practitioner

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who she saw really didn't feel much maybe a

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vague mass at 12 o'clock.

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Notably the patient has a

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fairly significant family history in multiple maternal

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relatives. So maternal Aunt maternal

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grade and maternal grandmother great-grandmother. Her mother

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did not have any history of

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breast cancer and actually had been tested for the bracha genes

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and was found to be negative.

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So again, this was a right palpable Mass.

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I'll just

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show you the

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right side here.

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So there's the BB and you can see she's very dense, and there's

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really nothing.

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very visible on the 2D mammogram

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And there's the mlo.

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We did do tomosynthesis. So I will.

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So again, we're going to be looking up in here. That's where the symptom.

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The lump is hopefully this will load.

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Okay, here we go.

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You can see maybe there's some an oval Mass

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there.

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But really not seeing much.

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I'll show the CC Tomo.

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Okay, again, we're looking at this 12 o'clock area.

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And there you can see these partially I would say obscured

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what margins we can

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see look pretty circumscribed and a dense round, Mass.

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So, of course we want to ultrasound.

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okay, and

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I'm going to just scroll through these ultrasound images.

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So here's what we're looking at.

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You can see very dark anechoic portion.

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Pretty well circumscribed margins and then this hypochoic portion.

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and

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we looked with very low flow sensitive settings to see

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if there was any flow in any of these peripheral hypo

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click portions, and we did not see any she had

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no abnormal lymph nodes.

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And here's a semi clip.

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Which I think shows the characteristics of this very well.

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Okay, and again, there was no blood flow in any

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of those peripheral parts.

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Okay, so can I have the polling question for case

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six?

3:21

Thank you.

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Okay. So what do you want to do with this patient? 38 year

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old palpable lump?

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So is it a complicated cyst to wanna

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try and aspirate it?

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Follow it or just go straight to YFC.

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Okay, great. So everybody wants to

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try to do.

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some more diagnostic

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stuff so

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it looks like either attempt to aspirate it and if it

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doesn't collapse biopsy it or just go straight to biopsy great.

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okay, so what we did is

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I actually was the one that did her biopsy.

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And I wanted to try and aspirate it first so

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I have an image here.

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This is actually.

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Me injecting lidocaine into the kind of capsule of

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it. So I'm going to play this for you.

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And I think it's really nicely shows that the anticoic

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part is just kind of swirling around but you can see there

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these hypochoic parts, which really aren't moving

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at all.

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Okay, and then I'll

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and this is my after I gave the

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lidocaine I attempted to aspirate.

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And you can see it did get smaller but there's definitely it did

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not collapse totally.

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So I went ahead and did a core biopsy.

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And this ended up being a triple negative

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high grade.

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invasive ductal carcinoma

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So you all made the right choice, so I

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was just going to show the MRI because I think it has some interesting.

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and typical

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features of high grade

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Invasive ductal. So this is the t2 sequence and

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not surprisingly especially given on that

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given the appearance on the ultrasound. There is too bright.

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material that probably represents necrosis

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You can see the marker clip from the biopsy.

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And the lesion is almost all T2 bright

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with some areas of very hyperintense T2,

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which probably corresponds to that necrotic

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material. But even the tumor itself is pretty

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T2 bright.

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And then this is the first post contrast.

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It did show some wash out and I'll just show you the

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basically, it shows Rim enhancement which also fits really

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nicely with the

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with the ultrasound appearance

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So you can see here this but the key differential here

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is that this Rim enhancement here. It's pretty

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smooth and uniform but here it becomes very thick and irregular.

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And near the top of it. It's they're going to regular so that all fits

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really nicely with the

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ultrasound images

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and she underwent neo-adjuvant chemotherapy

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and had a complete pathologic response.

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So good news for her.

Report

Faculty

Jennifer Kohr, MD

Diagnostic Radiology Residency Program Director

Virginia Mason Medical Center

Tags

Women's Health

Ultrasound

Mammography

MRI

Breast