The menopause transition brings complex physical and emotional changes that extend far beyond hot flashes, significantly impacting women's mental health and well-being. This comprehensive course explores the intricate interplay between hormonal shifts and psychological health during this transformative life stage. Healthcare professionals gain essential insights into how estrogen decline affects mood regulation, cognitive function, and emotional resilience, while learning to recognize and address mental health challenges commonly experienced during perimenopause and menopause. The curriculum examines the biological mechanisms linking hormonal changes to anxiety, depression, sleep disturbances, and cognitive changes, providing evidence-based assessment and intervention strategies. Participants explore interprofessional approaches to supporting comprehensive menopause care that integrates mental health considerations, enabling them to better support women navigating this transition. Perfect for healthcare providers seeking to enhance their understanding of menopause's psychological impact, this course delivers practical strategies for improved patient outcomes and more holistic care delivery.