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Mirizzi Syndrome

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Okay, so Mirizzi syndrome, this is next

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level, but that's why you're here.

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Mastering our profession is really learning the

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oddities that will be helpful clinically, which

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really establish dominance in our profession and

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allow us to make those diagnoses that are hard.

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That's what we're in it for.

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We're trying to do the hard things,

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not the easy, um, parts of radiology.

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So I really wanted to bring this case

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in because Mirizzi syndrome's a problem.

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It is a difficult clinical diagnosis.

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It's when you have this

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stone as in this diagram, either, uh, within

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the cystic duct itself or in the neck,

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compressing the hepatic ducts, resulting

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in intrahepatic biliary ductal dilatation.

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Not only is this something that may cause

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jaundice for your patients or other problems.

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This can be a surgical dilemma.

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These are dangerous.

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They can cause fistulas to the common bile duct.

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It can be a really high-level surgery.

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There can be a lot of adhesions, a lot

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of difficulties. Um, in our hospital,

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you want the OG surgeon in these cases.

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This is one of our high-level biliary surgeons.

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So if a patient has Mirizzi Syndrome, they're not

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goint to just send this to the acute trauma care team.

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This is goint to go to somebody who's

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specifically hepatobiliary trained,

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because of all those adhesions.

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If you tear the common bile duct, and let's be

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clear, the common bile duct, it's not that strong.

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So if you rip and tear that and you

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have to have some kind of anastomosis,

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you want the proper surgeon involved.

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So this is done

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very delicately at our institution, and this diagnosis

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is something that we don't wanna miss for our patients.

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Here's another case.

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I'm just goint to show you another case just so that

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you are aware of this entity, so, you know,

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to heighten the level of acuity to your clinicians.

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Again, Mirizzi syndrome.

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Um, these are all named after old dead

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white guys, so we always call it the DWG.

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And Mirizzi syndrome is when you have this echogenic

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obstructing stone at the porta hepatis causing

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intrahepatic biliary ductal dilatation.

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Here you can see that those ducts have

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those echogenic surroundings and are not,

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um, showing blood flow on the image here.

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Beautiful Mirizzi syndrome.

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Okay, let's side quest, side quest.

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Permission to side quest.

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Alright, dilated intrahepatic ducts.

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Here's a patient who's normal.

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You don't see the ducts at all, and in a

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normal patient, you won't see the bile ducts.

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Here is a patient who has mildly dilated,

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um, bile ducts and you can see that they're

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little circles on the side of the portal

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veins within the parenchyma of the liver.

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66 00:02:19,840 --> 00:02:22,900 Even a little bit more impressive in the left lobe here.

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This is a patient who has even more dramatic

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just 'cause I like to show you the drama.

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Intrahepatic biliary ductal dilatation.

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Here you can see the portal vein

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with that just tube of bile.

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Very, very dilated.

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You can imagine that this patient is likely very

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jaundiced, may have presented with itching or the like.

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The bile ducts in the portal triad are

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adjacent to the portal veins, and there can

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be the little tiny hepatic artery as well.

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So this is the normal findings of the portal

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triads with the hepatic veins centrally,

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then draining the liver into the heart.

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So,

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the portal triad has a lot going on, right?

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Like that's, that's actually a lot going on with

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the bile duct, the vein, and the artery as well.

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And also in this space, there's

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a lot of potential space.

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There are lymphatics and there are other

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soft tissue, uh, structures as well.

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Some of that connective tissue.

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So this is a space that has a lot of

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propensity for, um, developing oddities,

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one might say. Here's a patient who

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comes in with right upper quadrant pain,

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but they look a little bit different.

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Do we say this is dilated bile ducts?

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Look at this. This is not a tube on

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one side of the portal vein.

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Instead, these are small, low-attenuation

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fluid halos around the portal vein.

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Here again, we have a fluid

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halo around the portal vein.

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As we come down, we even have some

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fluid in the retroperitoneum here.

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Notice that this gallbladder, it is so thickened.

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Look how thick that wall is.

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This is the mucosa.

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This is the gallbladder wall.

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So this is a patient who has extreme

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gallbladder wall thickening and, um, a lot

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of fluid within the periportal regions.

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But unlike a patient with

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dilated bile ducts,

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this is periportal edema, and this is an

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entity to be very knowledgeable about because

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you will see it in a lot of your patients.

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Periportal edema is just basically fluid that

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has accumulated in that periportal region,

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in those portal triads. It's usually described as having

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halos, being halos of edema, and it's nonspecific.

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You can get periportal edema if

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you were over-fluid hydrated,

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if you have hepatitis, if you have

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right-sided

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heart failure, which is a really common reason,

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just because there's buildup of fluid in the liver.

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Anything where you have too much fluid, and I

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like to say that the gallbladder wall is usually

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very thick, almost too thick to be infected,

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and the gallbladder is usually not distended

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like you would see in acute cholecystitis.

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So this is another entity that frequently kind of

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gives you a little bit of confusion in the setting

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of a patient who has right upper quadrant pain; they

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can come in with right upper quadrant pain because

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even in the setting of congestive hepatopathy from

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right-sided heart failure,

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patients will feel discomfort from

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that pressure on their liver capsule.

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So be aware of periportal edema and how it looks

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different than intrahepatic biliary ductal dilatation.

Report

Faculty

Laura L Avery, MD

Assistant Professor of Emergency Radiology Harvard Medical School

Massachusetts General Hosptial

Tags

Ultrasound

Other Biliary

Gastrointestinal (GI)

Gallbladder

Emergency

Body

Acquired/Developmental

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